公开(公告)号：EP3235502A2

公开(公告)日：2017-10-25

申请号：EP15870223.3

申请日：2015-12-03

申请人： Dong-A ST Co., Ltd.

发明人： CHOI, Sang Zin ,  SOHN, Mi Won ,  GO, Hyo Sang ,  RYU, Ja Young ,  JEONG, Jin Seok ,  CHOI, Song Hyen ,  KIM, Eun Jin ,  CHO, Young Woong ,  KIM, So Young

IPC分类号： A61K36/076 ,  A61P25/28 ,  A61P25/16 ,  A61P25/00

摘要： The present invention relates to a pharmaceutical composition and a food composition for preventing or ameliorating degenerative neurological disease comprising Poria cocos peel extract for preventing, or treating neurodegenerative disorders. Poria cocos peel extract which is the active ingredients contained in the composition of the present invention, has a memory ameliorating activity through inhibiting of acetylcholine esterase and a neuroprotective effect and neuron protection by inhibiting the formation of beta amyloid and tau phosphorylation and promoting NGF production. Thus, the present invention may be useful as a pharmaceutical composition for preventing or treating degenerative neurological diseases, or as a health food for the above purpose.

摘要翻译： 本发明涉及用于预防或缓解退行性神经疾病的药物组合物和食物组合物，其包含茯苓剥离提取物用于预防或治疗神经变性疾病。 作为本发明组合物中含有的活性成分的茯苓剥皮提取物通过抑制乙酰胆碱酯酶而具有记忆改善活性，并且通过抑制β淀粉状蛋白和τ磷酸化的形成并促进NGF产生而具有神经保护作用和神经元保护。 因此，本发明可用作用于预防或治疗退行性神经疾病的药物组合物，或用作上述目的的保健食品。

公开(公告)号：EP3235503A2

公开(公告)日：2017-10-25

申请号：EP15870222.5

申请日：2015-12-03

申请人： Dong-A ST Co., Ltd.

发明人： CHOI, Sang Zin ,  SOHN, Mi Won ,  GO, Hyo Sang ,  RYU, Ja Young ,  JEONG, Jin Seok ,  CHOI, Song Hyen ,  KIM, Eun Jin ,  CHO, Young Woong ,  KIM, So Young

IPC分类号： A61K36/605 ,  A61K36/076 ,  A23L33/10 ,  A61P25/28 ,  A61P25/00

CPC分类号： A61K36/076 ,  A61K36/605

摘要： The present invention relates to a composition comprising the mixed extract of mulberry and Poria cocos peel for preventing, improving or treating neurodegenerative disorders. The mixed extract of mulberry and Poria cocos peel which is the active ingredients contained in the composition of the present invention, has a memory improving activity through inhibiting of acetylcholine esterase and a neuroprotective effects and neuron protection by inhibiting the formation of beta amyloid and tau phosphorylation and promoting NGF production. Thus, the present invention may be useful as a pharmaceutical composition for preventing or treating degenerative neurological diseases, or as a health food for the above purpose.

摘要翻译： 本发明涉及包含桑树和茯苓皮的混合提取物用于预防，改善或治疗神经变性疾病的组合物。 作为本发明组合物中所含活性成分的桑树和茯苓皮的混合提取物通过抑制乙酰胆碱酯酶和通过抑制β淀粉状蛋白和τ磷酸化的形成而具有神经保护作用和神经元保护，具有记忆改善活性 并促进NGF的产生。 因此，本发明可用作用于预防或治疗退行性神经疾病的药物组合物，或用作上述目的的保健食品。