公开(公告)号：EP0927171A1

公开(公告)日：1999-07-07

申请号：EP97941068.0

申请日：1997-09-15

申请人： Du Pont Pharmaceuticals Company

发明人： ARVANITIS, Argyrios, Georgios ,  OLSON, Richard, Eric ,  ARNOLD, Charles, R., III ,  FRIETZE, William, E.

IPC分类号： A61K31 ,  A61P25 ,  C07D241 ,  C07D253 ,  C07D401 ,  C07D405

CPC分类号： C07D241/20 ,  C07D241/18 ,  C07D253/07 ,  C07D401/12 ,  C07D405/12

摘要： Corticotropin releasing factor (CRF) antagonists of Formula (I), and their use in treating psychiatric disorders and neurological diseases including major depression, anxiety-related disorders, post-traumatic stress disorders, supranuclear palsy and eating disorders.

公开(公告)号：EP1049699A1

公开(公告)日：2000-11-08

申请号：EP99904382.1

申请日：1999-01-28

申请人： Du Pont Pharmaceuticals Company

发明人： HE, Liqi ,  GILLIGAN, Paul ,  CHORVAT, Robert ,  ARVANITIS, Argyrios, Georgios

IPC分类号： C07D487/04 ,  A61K31/495

CPC分类号： C07D487/04

摘要： Corticotropin releasing factor (CRF) antagonists of formula (I) or (II) and their use in treating anxiety, depression, and other psychiatric, neurological disorders as well as treatment of immunological, cardiovascular or heart-related diseases and colonic hypersensitivity associated with psychopathological disturbance and stress.

公开(公告)号：EP0927171B1

公开(公告)日：2002-02-20

申请号：EP97941068.5

申请日：1997-09-15

申请人： Du Pont Pharmaceuticals Company

发明人： ARVANITIS, Argyrios, Georgios ,  OLSON, Richard, Eric ,  ARNOLD, Charles, R., III ,  FRIETZE, William, E.

IPC分类号： C07D241/20 ,  A61K31/495 ,  C07D401/12 ,  C07D405/12 ,  C07D253/07 ,  C07D241/18

CPC分类号： C07D241/20 ,  C07D241/18 ,  C07D253/07 ,  C07D401/12 ,  C07D405/12

摘要： Corticotropin releasing factor (CRF) antagonists of Formula (I), and their use in treating psychiatric disorders and neurological diseases including major depression, anxiety-related disorders, post-traumatic stress disorders, supranuclear palsy and eating disorders.

公开(公告)号：EP0935601A2

公开(公告)日：1999-08-18

申请号：EP97916991.0

申请日：1997-03-25

申请人： Du Pont Pharmaceuticals Company

发明人： BAKTHAVATCHALAM, Rajagopal ,  ARVANITIS, Argyrios, Georgios ,  BECK, James, Peter ,  CAIN, Gary, Avonn ,  CHORVAT, Robert, John ,  GILLIGAN, Paul, Joseph ,  OLSON, Richard, Eric

IPC分类号： C07D239 ,  C07D473 ,  A61K31 ,  A61P1 ,  A61P15 ,  A61P25 ,  A61P29 ,  A61P37 ,  A61P43 ,  C07D471 ,  C07D487 ,  C07D513

CPC分类号： C07D471/04 ,  C07D487/04 ,  C07D513/04

摘要： Corticotropin releasing factor (CRF) antagonists of formula (I) or formula (II): and their use in treating anxiety, depression, and other psychiatric and neurological disorders.