公开(公告)号：EP2729175A1

公开(公告)日：2014-05-14

申请号：EP12810688.7

申请日：2012-07-09

申请人： Duke University ,  Immunolight, LLC

发明人： BOURKE, Frederic, A. ,  WALDER, Harold ,  FATHI, Zakaryae ,  THERIEN, Michael J. ,  DEWHIRST, Mark W. ,  STANTON, Ian Nicholas ,  AYRES, Jennifer, Ann ,  FELS, Diane, Renee ,  HERBERT, Joseph, A.

IPC分类号： A61K41/00

CPC分类号： A61N5/062 ,  A61K41/0085 ,  A61N5/0622 ,  A61N5/1077 ,  A61N2005/0661 ,  A61N2005/1091 ,  A61N2005/1098

摘要： A system and method for light stimulation within a medium. The system has a reduced-voltage x-ray source configured to generate x-rays from a peak applied cathode voltage at or below 105 kVp, and a plurality of energy-emitting particles in the medium which, upon radiation from the x-ray source, radiate at a first lower energy than the x-ray source to interact with at least one photoactivatable agent in the medium. The method introduces the plurality of energy-emitting particles into the medium, radiates the energy-emitting particles in the medium with x-rays generated from a peak applied cathode voltage at or below 105 kVp; and emits a lower energy than the x-ray source to interact with the medium or with at least one photoactivatable agent in the medium.