公开(公告)号：EP0973725A2

公开(公告)日：2000-01-26

申请号：EP97911385.9

申请日：1997-10-16

申请人： EGIS GYOGYSZERGYAR RT.

发明人： GACSALYI, István ,  KLEBOVICH, Imre ,  BUDAI, Zoltán ,  LUKACS, Gyula ,  KAUFMANNE BOJTI, Erzsébet ,  SCHMIDT, Eva ,  GYERTYAN, István ,  BILKEI GORZO, András ,  BLASKO, Gábor ,  ABERMANN, Miklos ,  BALOGHNE NEMES, Katalin ,  GREZAL, Gyula ,  EGYED, András

IPC分类号： C07C217/00

CPC分类号： C07C217/12 ,  C07C2602/42 ,  Y02P20/55

摘要： The new compound of Formula (I) and salts thereof possess valuable anxiolytic properties.

公开(公告)号：EP1648451A2

公开(公告)日：2006-04-26

申请号：EP04743730.6

申请日：2004-06-30

申请人： EGIS GYOGYSZERGYAR RT.

发明人： FEKETE, Pál ,  VIRGULA, Judit ,  FURDYGA, Eva ,  LEVENTISZNE HUSZAR, Magdolna ,  KLEBOVICH, Imre ,  BALOGHNE NEMES, Katalin

IPC分类号： A61K31/4196

CPC分类号： A61K31/4196 ,  A61K9/4858 ,  A61K9/4866 ,  A61K9/5015

摘要： The object of the invention is to provide fluconazole containing capsules with improved active ingredient release. The in vitro dissolution as well as in vivo absorption of the fluconazole capsules according to the invention is faster and more consistent than those of commercial compositions containing fluconazole. The invention is based on the fact that granulation of fluconazole particles with an agent capable to provide hydrophilic surface, e.g. lactose, to said particles results in fast an consistent release of the active ingredient. In this way, capsules according to the invention are suitable to provide enhanced absorption of said active ingredient.

公开(公告)号：EP0973725B1

公开(公告)日：2002-06-19

申请号：EP97911385.9

申请日：1997-10-16

申请人： EGIS GYOGYSZERGYAR RT.

发明人： GACSALYI, István ,  KLEBOVICH, Imre ,  BUDAI, Zoltán ,  LUKACS, Gyula ,  KAUFMANNE BOJTI, Erzsébet ,  SCHMIDT, Eva ,  GYERTYAN, István ,  BILKEI GORZO, András ,  BLASKO, Gábor ,  ABERMANN, Miklos ,  BALOGHNE NEMES, Katalin ,  GREZAL, Gyula ,  EGYED, András

IPC分类号： C07C217/00

CPC分类号： C07C217/12 ,  C07C2602/42 ,  Y02P20/55