公开(公告)号：EP0289342A3

公开(公告)日：1989-01-25

申请号：EP88303918.2

申请日：1988-04-29

申请人： ELAN TRANSDERMAL LIMITED

发明人： Bannon, Yvonne Brigid ,  Corish, John ,  Corrigan, Owen Ignatius ,  Geoghegan, Edward James ,  Masterson, Joseph G.

IPC分类号： A61K31/465 ,  A61K47/00 ,  A61L15/00

CPC分类号： A61K9/7069 ,  A61K9/7023 ,  A61K9/7084 ,  A61K31/465 ,  A61K47/34 ,  A61K47/36 ,  A61K47/42 ,  Y10S514/813 ,  Y10S514/922 ,  Y10S514/936 ,  Y10S514/944 ,  Y10S514/946 ,  Y10S514/964 ,  Y10S514/965 ,  Y10S514/974

摘要： A preparation for the once-daily, percutaneous administration of nicotine comprises nicotine uniformly distributed in a solid, semi-solid or mucilaginous medium which can be placed in intimate contact with the skin, the solid, semi-solid or mucilaginous medium is formed by adding a given amount of nicotine to a solution of a solidifying or gel-forming agent or mixture thereof in a suitable solvent or mixture of solvents and mixing or heating the mixture thereby obtained so as to form the solid, semi-solid or mucilaginous medium. The preparation can be used in a method of treating withdrawal symptoms associated with smoking cessation and for combating the psychological dependence that occurs through frequent smoking.

公开(公告)号：EP0289342B1

公开(公告)日：1998-01-07

申请号：EP88303918.2

申请日：1988-04-29

申请人： ELAN TRANSDERMAL LIMITED

发明人： Bannon, Yvonne Brigid ,  Corish, John ,  Corrigan, Owen Ignatius ,  Geoghegan, Edward James ,  Masterson, Joseph G.

IPC分类号： A61K31/465 ,  A61K47/00 ,  A61L15/00

CPC分类号： A61K9/7069 ,  A61K9/7023 ,  A61K9/7084 ,  A61K31/465 ,  A61K47/34 ,  A61K47/36 ,  A61K47/42 ,  Y10S514/813 ,  Y10S514/922 ,  Y10S514/936 ,  Y10S514/944 ,  Y10S514/946 ,  Y10S514/964 ,  Y10S514/965 ,  Y10S514/974

公开(公告)号：EP0289342A2

公开(公告)日：1988-11-02

申请号：EP88303918.2

申请日：1988-04-29

申请人： ELAN TRANSDERMAL LIMITED

发明人： Bannon, Yvonne Brigid ,  Corish, John ,  Corrigan, Owen Ignatius ,  Geoghegan, Edward James ,  Masterson, Joseph G.

IPC分类号： A61K31/465 ,  A61K47/00 ,  A61L15/00

CPC分类号： A61K9/7069 ,  A61K9/7023 ,  A61K9/7084 ,  A61K31/465 ,  A61K47/34 ,  A61K47/36 ,  A61K47/42 ,  Y10S514/813 ,  Y10S514/922 ,  Y10S514/936 ,  Y10S514/944 ,  Y10S514/946 ,  Y10S514/964 ,  Y10S514/965 ,  Y10S514/974

摘要： A preparation for the once-daily, percutaneous administration of nicotine comprises nicotine uniformly distributed in a solid, semi-solid or mucilaginous medium which can be placed in intimate contact with the skin, the solid, semi-solid or mucilaginous medium is formed by adding a given amount of nicotine to a solution of a solidifying or gel-forming agent or mixture thereof in a suitable solvent or mixture of solvents and mixing or heating the mixture thereby obtained so as to form the solid, semi-solid or mucilaginous medium.
The preparation can be used in a method of treating withdrawal symptoms associated with smoking cessation and for combating the psychological dependence that occurs through frequent smoking.

摘要翻译： 一种用于烟碱的每日一次，经皮给药制剂包括烟碱均匀地分布在可以在与皮肤紧密接触被放置在固体，半固体或粘液介质，固体，半固体或粘液介质通过添加FORMED 尼古丁到凝固或溶液的给定量的凝胶形成中溶剂的合适的溶剂或它们的混合物剂或混合物和混合或加热该混合物由此获得以形成固体，半固体或粘液平台。 该制剂可以治疗与戒烟有关的戒断症状的方法，并打击了依赖心理被用来做了发生通过频繁的吸烟。