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公开(公告)号：EP0100605A1
公开(公告)日：1984-02-15
申请号：EP83303866.4
申请日：1983-07-04
CPC分类号： C12R1/465 , A23K20/195 , A23K50/30 , A61K38/00 , C07K9/008 , Y10S435/886 , Y10S930/19 , Y10S930/27
摘要： Antibiotic A47934 of formula
is produced by submerged, aerobic fermentation of new Streptomyces toyocaensis NRRL 15009 in a culture containing assimilable sources of carbon, nitrogen, and inorganic salts, and is active against gram-positive bacteria in vitro and in vivo, and also promotes growth in poultry and swine and serves to enhance feed efficiency in ruminant animals having a developed rumen.-
公开(公告)号：EP0209971B1
公开(公告)日：1991-03-06
申请号：EP86303977.2
申请日：1986-05-27
IPC分类号： C07D493/10 , C12P17/06 , A23K1/17
CPC分类号： C07H19/01 , A23K20/195 , A23K50/30 , C12P17/181 , C12P19/44 , C12P19/445 , C12R1/465
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公开(公告)号：EP0305086A3
公开(公告)日：1990-04-18
申请号：EP88307431.2
申请日：1988-08-11
IPC分类号： C07H15/04 , C07D407/14 , A61K31/70 , A23K1/17 , C12P19/44
CPC分类号： C07D407/14 , C12P17/16 , C12R1/03
摘要： New polyether antibiotic A80577, which has the Formula its acyl ester and alkyl ether derivatives, and salts thereof, are useful antibacterial agents and increase feed-utilization efficiency in animals. Methods of making A80577 by culture of Actinomadura verrucosospora , NRRL 18236, and compositions containing A80577 compound also are provided.
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公开(公告)号：EP0265071A1
公开(公告)日：1988-04-27
申请号：EP87308219.2
申请日：1987-09-17
发明人： Hamill, Robert L. , Mabe, James Albert , Mahoney, David Francis , Nakatsukasa, Walter Mitsuo , Yao, Raymond Che-Fong
CPC分类号： C12R1/365 , A61K38/00 , C07K9/008 , Y10S435/872
摘要： New glycopeptide antibiotic A82846, comprising A82846A, A82846B and A82846C, is produced by Nocardia orientalis strains NRRL 18098, NRRL 18099 and NRRL 18100. The A82846 antibiotics have activity against Gram-positive bacteria comparable to that of vancomycin.
摘要翻译： 包含A82846A，A82846B和A82846C的新糖肽抗生素A82846由诺卡氏菌（Nocardia orientalis）NRRL 18098，NRRL 18099和NRRL 18100产生.A82846抗生素具有与万古霉素相当的革兰氏阳性菌的活性。
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公开(公告)号：EP0184291A2
公开(公告)日：1986-06-11
申请号：EP85307186.8
申请日：1985-10-08
CPC分类号： C07H19/01 , A23K20/195 , A23K50/30 , C12P19/445 , C12P19/60 , C12R1/03
摘要： New polyether antibiotic A80190, its acyl and alkyl ester, acyl ester and urethane derivatives, and salts thereof, are useful antibacterial and anticoccidial agents and increase feed-utilization efficiency in animals. Methods of making A80190 by culture of Actinomodura oligospora NRRL 15877 or NRLL 15878 and synergistic compositions of the A80190 compounds with nicarbazin, 4,4'-dinitrocarbanilide, certain napthalenamine and benzenamine compounds and metichlorpindol are also provided.
摘要翻译： 新的聚醚抗菌素A80190，其酰基和烷基酯，酰基酯和氨基甲酸酯衍生物及其盐是有用的抗菌和抗球虫剂，并增加动物的饲料利用效率。 还提供了通过培养放线菌寡聚核苷酸NRRL 15877或NRLL 15878制备A80190的方法，以及A80190化合物与氨基脲，4,4'-二硝基甲苯胺，某些萘胺和苯胺化合物和二氯代吲哚酚的协同组合物。
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6.发明公开Mixture of antibiotics designated by A-21978, process for its production, their pharmaceutical compositions and producing microorganism 失效提到的A-21978抗生素混合物，它们的制备方法，其药物组合物和生产微生物。
公开(公告)号：EP0010421A1
公开(公告)日：1980-04-30
申请号：EP79302216.1
申请日：1979-10-15
IPC分类号： C12P21/04 , A61K37/02 , C07C233/00
CPC分类号： C12R1/465 , A61K38/00 , C07K7/08 , Y10S930/19 , Y10S930/27
摘要： Antibiotic A-21978 mixtures, in particular the A-21978C mixture, comprising microbiologically active, related factors Co, C 1 , C 2 , C 3 , C 4 , and C s . A-21978 mixture and A-21978C mixture are produced by submerged aerobic fermentation of Streptomyces roseosporus NRRL 11379. The individual A-29178C factors are separated and isolated by chromatography. The A-21978 and A-2f978C mixtures; the A-21978C factors; and pharmaceutically acceptable salts thereof are antibacterial agents and improve growth promotion in poultry.
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公开(公告)号：EP0001709A3
公开(公告)日：1979-05-16
申请号：EP78300514
申请日：1978-10-17
IPC分类号： C12D09/14 , C07D493/20 , A23K01/17 , C07D311/00 , C07D307/00
CPC分类号： C07D493/10 , C07H19/01 , C12P17/181 , C12R1/485 , Y10S435/889
摘要： Deoxynarasin antibiotic complex, comprising 20-deoxynarasin and 20-deoxy-epi-17- narasin, is produced by submerged aerobic fermentation of Streptomyces aureofaciens NRRL 11181. 20-Deoxynarasin and 20-deoxy-epi-17- narasin are separated and isolated by chromatography. The deoxynarasin complex, 20-deoxynarasin and 20-deoxy-epi-17-narasin are antibacterial and anticoccidial agents and also increase feed-utilization efficiency in ruminants.
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公开(公告)号：EP0184291B1
公开(公告)日：1992-05-27
申请号：EP85307186.8
申请日：1985-10-08
CPC分类号： C07H19/01 , A23K20/195 , A23K50/30 , C12P19/445 , C12P19/60 , C12R1/03
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公开(公告)号：EP0422818A1
公开(公告)日：1991-04-17
申请号：EP90310770.4
申请日：1990-10-02
CPC分类号： A61K31/70 , A23K20/195 , C07H19/01 , C12P19/60 , A61K31/505 , A61K31/17 , A61K31/135 , A61K2300/00
摘要： New polyether antibiotic A80789 (I), its acyl ester, alkyl ester, and alkyl ether derivatives, and salts thereof, are useful as antibacterial and anticoccidial agents and increase feed-utilization efficiency in animals. Methods of making A80789 by culture of Streptomyces hygroscopicus NRRL 18513, and combinations of the A80789 compounds with nicarbazin, 4,4'-dinitrocarbanilide, certain napthalenamine and benzenamine compounds and are also provided.
摘要翻译： 新型聚醚抗菌素A80789（I），其酰基酯，烷基酯和烷基醚衍生物及其盐可用作抗细菌剂和抗球虫剂，并增加动物的饲料利用效率。 通过培养吸水链霉菌NRRL 18513制备A80789的方法，以及A80789化合物与氨基脲，4,4'-二硝基甲苯胺，某些萘胺和苯胺化合物的组合。
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公开(公告)号：EP0334632A3
公开(公告)日：1990-10-24
申请号：EP89302836.5
申请日：1989-03-22
CPC分类号： C07K4/04 , A23K20/195 , A61K38/00 , C12P1/06 , C12R1/465
摘要： New antibiotic A80509 is produced by Streptomyces mutabilis strain NRRL 18269. A80509, its C₁-C₇-alkyl ester derivatives and salts, are useful antibacterial and anticoccidial agents and improve feed efficiency and growth in animals.
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