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1.发明授权6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS 有权6-取代的-2,3,4,5-四氢-1H-苯并[d]氮杂作为对5-HT2C受体激动剂
公开(公告)号：EP1720836B1
公开(公告)日：2014-04-16
申请号：EP05723397.5
申请日：2005-02-18
发明人： ALLEN, John, Gordon , BRINER, Karin , COHEN, Michael, Philip , GALKA, Christopher, Stanley , HELLMAN, Sarah, Lynne , MARTINEZ-GRAU, Maria Angeles , REINHARD, Matthew, Robert , RODRIGUEZ, Michael, John , ROTHHAAR, Roger, Ryan , TIDWELL, Michael, Wade , VICTOR, Frantz , WILLIAMS, Andrew Caerwyn , ZHANG, Deyi , LEE, Wai-Man , SIEDEM, Christopher, Stephen , SINGH, Ajay ,
IPC分类号： C07D223/16 , C07D401/12 , C07D417/12 , C07D413/12 , C07D403/12 , C07D409/12 , C07D405/12 , C07D413/14 , C07D417/06 , C07D403/06 , A61K31/55 , A61P25/22 , A61P25/24 , A61P25/30 , A61P3/04
CPC分类号： C07D223/16 , C07D401/12 , C07D403/06 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/06 , C07D417/12
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2.发明公开6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS 有权6-取代的-2,3,4,5-四氢-1H-苯并[d]氮杂作为对5-HT2C受体激动剂
公开(公告)号：EP1720836A1
公开(公告)日：2006-11-15
申请号：EP05723397.5
申请日：2005-02-18
发明人： ALLEN, John, Gordon , BRINER, Karin , COHEN, Michael, Philip , GALKA, Christopher, Stanley , HELLMAN, Sarah, Lynne , MARTINEZ-GRAU, Maria Angeles , REINHARD, Matthew, Robert , RODRIGUEZ, Michael, John , ROTHHAAR, Roger, Ryan , TIDWELL, Michael, Wade , VICTOR, Frantz , WILLIAMS, Andrew Caerwyn , ZHANG, Deyi , BOYD, Steven, Armen , CONWAY, Richard, Gerard , DEO, Arundhati, S. , LEE, Wai-Man , SIEDEM, Christopher, Stephen , SINGH, Ajay ,
IPC分类号： C07D223/16 , C07D401/12 , C07D417/12 , C07D413/12 , C07D403/12 , C07D409/12 , C07D405/12 , C07D413/14 , C07D417/06 , C07D403/06 , A61K31/55 , A61P25/22 , A61P25/24 , A61P25/30 , A61P3/04
CPC分类号： C07D223/16 , C07D401/12 , C07D403/06 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/06 , C07D417/12
摘要： The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula I as selective 5-HT 2C receptor agonists for the treatment of 5-HT 2C associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety: where: R 6 is -S-L-R 15 and other substituents are as defined in the specification.
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