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1.发明公开Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes and 3-aminochromanes 失效Ringsubstituierte 2-氨基-1,2,3,4-四氢化萘和3-氨基荧光素
公开(公告)号：EP0712837A2
公开(公告)日：1996-05-22
申请号：EP96200393.5
申请日：1992-02-03
IPC分类号： C07C225/20 , C07C211/42 , C07D311/58
CPC分类号： C07D261/10 , C07C225/20 , C07C2602/10 , C07D261/08 , C07D261/12 , C07D311/58 , C07D413/10 , Y02P20/582
摘要： The present invention provides novel ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes which exhibit binding activity at the serotonin 1A receptor.
摘要翻译： 本发明提供了在5-羟色胺1A受体上表现出结合活性的新的环取代的2-氨基-1,2,3,4-四氢萘和3-氨基色烷。
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2.发明授权Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes and 3-aminochromanes 失效Ringsubstituierte 2-氨基-1,2,3,4-四氢化萘和3-氨基荧光素
公开(公告)号：EP0712837B1
公开(公告)日：2000-10-25
申请号：EP96200393.5
申请日：1992-02-03
IPC分类号： C07C225/20 , C07C211/42 , C07D311/58
CPC分类号： C07D261/10 , C07C225/20 , C07C2602/10 , C07D261/08 , C07D261/12 , C07D311/58 , C07D413/10 , Y02P20/582
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公开(公告)号：EP0722941A2
公开(公告)日：1996-07-24
申请号：EP96300286.0
申请日：1996-01-15
发明人： Audia, James E. , Hibschman, David J. , Krushinski Jr., Joseph H. , Mabry, Thomas E. , Nissen, Jeffrey S. , Rasmussen, Kurt , Rocco, Vincent P. , Schaus, John M. , Thompson, Dennis C. , Wong, David T.
IPC分类号： C07D401/12 , C07D403/12 , C07D401/14 , C07D403/14 , C07D471/10 , C07D498/04 , C07D513/04 , A61K31/44 , A61K31/445 , A61K31/495
CPC分类号： C07D209/08 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D471/08 , C07D471/10 , C07D491/10 , C07D495/10 , C07D513/04
摘要： A series of hetero-oxy alkanamines are effective pharmaceuticals for the treatment of conditions related to or affected by the reuptake of serotonin and by the serotonin 1 A receptor. The compounds are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal, and for the treatment of depression and other conditions for which serotonin reuptake inhibitors are used.
摘要翻译： 一系列异烷基链烷胺是用于治疗与5-羟色胺和5-羟色胺1A受体再摄取相关或受其影响的病症的有效药物。 该化合物特别可用于缓解尼古丁和烟草戒断的症状，以及治疗抑郁症和使用5-羟色胺再摄取抑制剂的其它病症。
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公开(公告)号：EP0722941A3
公开(公告)日：2000-04-12
申请号：EP96300286.0
申请日：1996-01-15
发明人： Audia, James E. , Hibschman, David J. , Krushinski Jr., Joseph H. , Mabry, Thomas E. , Nissen, Jeffrey S. , Rasmussen, Kurt , Rocco, Vincent P. , Schaus, John M. , Thompson, Dennis C. , Wong, David T.
IPC分类号： C07D401/12 , C07D403/12 , C07D401/14 , C07D403/14 , C07D471/10 , C07D498/04 , C07D513/04 , A61K31/44 , A61K31/445 , A61K31/495
CPC分类号： C07D209/08 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D471/08 , C07D471/10 , C07D491/10 , C07D495/10 , C07D513/04
摘要： A series of hetero-oxy alkanamines are effective pharmaceuticals for the treatment of conditions related to or affected by the reuptake of serotonin and by the serotonin 1 A receptor. The compounds are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal, and for the treatment of depression and other conditions for which serotonin reuptake inhibitors are used.
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5.发明公开Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes and 3-aminochromanes 失效环取代的2-氨基-1,2,3,4- tetrahydronaphtahline和3-氨基苯并二氢吡喃
公开(公告)号：EP0712837A3
公开(公告)日：1997-05-21
申请号：EP96200393.5
申请日：1992-02-03
IPC分类号： C07C225/20 , C07C211/42 , C07D311/58
CPC分类号： C07D261/10 , C07C225/20 , C07C2602/10 , C07D261/08 , C07D261/12 , C07D311/58 , C07D413/10 , Y02P20/582
摘要： The present invention provides novel ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes which exhibit binding activity at the serotonin 1A receptor.
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