专利检索 ap:("ENYO Pharma" OR "Institut National de la Santé et de la Recherche Médicale (INSERM)" OR "Centre National de la Recherche Scientifique" OR "Centre Léon Bérard" OR "Université Claude Bernard Lyon 1") AND inv:"DURANTEL, David" 第 1 页

1.

发明公开
SYNERGISTIC EFFECT OF A FXR AGONIST AND IFN FOR THE TREATMENT OF HBV INFECTION 审中-公开

公开(公告)号：EP4277622A1

公开(公告)日：2023-11-22

申请号：EP22701183.0

申请日：2022-01-13

申请人： ENYO Pharma , Institut National de la Santé et de la Recherche Médicale (INSERM) , Centre National de la Recherche Scientifique , Centre Léon Bérard , Université Claude Bernard Lyon 1

发明人： DARTEIL, Raphaël , SCALFARO, Pietro , VONDERSCHER, Jacky , ROY, Elise , DURANTEL, David

IPC分类号： A61K31/42 , A61K31/46 , A61K38/21 , A61K45/00 , A61P31/20

2.

发明公开
USE OF FXR AGONISTS FOR TREATING AN INFECTION BY HEPATITIS D VIRUS 审中-公开

公开(公告)号：EP4090327A1

公开(公告)日：2022-11-23

申请号：EP21700866.3

申请日：2021-01-14

申请人： Institut National de la Santé et de la Recherche Médicale (INSERM) , Ecole Normale Supérieure de Lyon , UNIVERSITE CLAUDE BERNARD - LYON 1 , Centre national de la recherche scientifique , ENYO Pharma

发明人： DARTEIL, Raphaël , LUCIFORA, Julie , DURANTEL, David , RAMIERE, Christophe , LACOMBE, Benoît , LOTTEAU, Vincent , ANDRE, Patrice

IPC分类号： A61K31/167 , A61K31/397 , A61K31/4045 , A61K31/4162 , A61K31/42 , A61K31/423 , A61K31/426 , A61K31/439 , A61K31/4439 , A61K31/4545 , A61K31/496 , A61K31/513 , A61K31/55 , A61K31/575 , A61K31/675 , A61K31/7056 , A61K31/7072 , A61K31/708 , A61K31/7088 , A61K38/21 , A61P31/14

3.

发明公开
METHODS FOR TREATING HEPATITIS B VIRUS (HBV) INFECTION 审中-公开

公开(公告)号：EP3773575A1

公开(公告)日：2021-02-17

申请号：EP18782681.3

申请日：2018-09-27

申请人： INSERM (Institut National de la Santé et de la Recherche Médicale) , Université Claude Bernard Lyon 1 , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS- , Centre Leon Berard , University Of British Columbia , Socpra Sciences Sante et Humaine S E C

发明人： SALVETTI, Anna , DURANTEL, David , CHABROLLES, Hélène , LAHLALI, Tomas , GRIERSON, David , CHABOT, Benoit

IPC分类号： A61K31/4439 , A61P31/20

4.

发明公开
URIDINE DERIVATIVES AS ANTIVIRAL DRUGS AGAINST A FLAVIVIRIDAE, ESPECIALLY HCV 审中-公开
标题翻译：尿苷衍生物作为针对黄病毒科病毒的抗病毒剂; 特别是HCV

公开(公告)号：EP1827457A1

公开(公告)日：2007-09-05

申请号：EP05824567.1

申请日：2005-12-22

申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) Etablissement Public

发明人： AUCAGNE, Vincent , ESCURET, Vanessa , ZOULIM, Fabien , DURANTEL, David , TREPO, Christian , AGROFOGLIO, Luigi , JOUBERT, Nicolas , AMBLARD, Franck

IPC分类号： A61K31/70 , A61P31/12

CPC分类号： A61K31/70

摘要： The invention relates to the use of an uridine derivative of formula (I) : wherein - R1 represents monohalogenated alkynyl or dihalogenated alkenyl; - R2 is chosen from among hydrogen, hydroxyl, O-alkyl, O-CO alkyl and halogen; - R3 is chosen from among hydrogen, hydroxyl, O-alkyl, O-CO alkyl, halogen, SH, S-alkyl and N3; and - R4 is chosen from among hydroxyl, O-alkyl, O-CO alkyl, O-phosphate, O-diphosphate, O-triphosphate and O phosphonate, as well as its possible tautomers, its possible pharmaceutically acceptable addition salts with an acid or a base, and its N-oxide forms, for the preparation of a drug having antiviral activity against a Flaviviridae.

5.

发明公开
STRONG POTENTIATION OF TLR3 AGONISTS EFFECTS USING FXR AGONISTS AS A COMBINED TREATMENT 审中-公开

公开(公告)号：EP4329761A1

公开(公告)日：2024-03-06

申请号：EP22725888.6

申请日：2022-04-28

申请人： ENYO Pharma

发明人： DARTEIL, Raphaël , DURANTEL, David

IPC分类号： A61K31/496 , A61K31/713 , A61K45/06 , A61P1/04 , A61P19/02 , A61P31/12 , A61P31/14 , A61P35/00 , A61P35/02 , A61P37/00