专利检索 ap:("Institut National de la Santé et de la Recherche Médicale (INSERM)" OR "Ecole Normale Supérieure de Lyon" OR "UNIVERSITE CLAUDE BERNARD - LYON 1" OR "Centre national de la recherche scientifique" OR "ENYO Pharma") AND inv:"DURANTEL, David" 第 1 页

1.

发明公开
USE OF FXR AGONISTS FOR TREATING AN INFECTION BY HEPATITIS D VIRUS 审中-公开

公开(公告)号：EP4090327A1

公开(公告)日：2022-11-23

申请号：EP21700866.3

申请日：2021-01-14

申请人： Institut National de la Santé et de la Recherche Médicale (INSERM) , Ecole Normale Supérieure de Lyon , UNIVERSITE CLAUDE BERNARD - LYON 1 , Centre national de la recherche scientifique , ENYO Pharma

发明人： DARTEIL, Raphaël , LUCIFORA, Julie , DURANTEL, David , RAMIERE, Christophe , LACOMBE, Benoît , LOTTEAU, Vincent , ANDRE, Patrice

IPC分类号： A61K31/167 , A61K31/397 , A61K31/4045 , A61K31/4162 , A61K31/42 , A61K31/423 , A61K31/426 , A61K31/439 , A61K31/4439 , A61K31/4545 , A61K31/496 , A61K31/513 , A61K31/55 , A61K31/575 , A61K31/675 , A61K31/7056 , A61K31/7072 , A61K31/708 , A61K31/7088 , A61K38/21 , A61P31/14

2.

发明公开
SYNERGISTIC EFFECT OF A FXR AGONIST AND IFN FOR THE TREATMENT OF HBV INFECTION 审中-公开

公开(公告)号：EP4277622A1

公开(公告)日：2023-11-22

申请号：EP22701183.0

申请日：2022-01-13

申请人： ENYO Pharma , Institut National de la Santé et de la Recherche Médicale (INSERM) , Centre National de la Recherche Scientifique , Centre Léon Bérard , Université Claude Bernard Lyon 1

发明人： DARTEIL, Raphaël , SCALFARO, Pietro , VONDERSCHER, Jacky , ROY, Elise , DURANTEL, David

IPC分类号： A61K31/42 , A61K31/46 , A61K38/21 , A61K45/00 , A61P31/20

3.

发明公开
URIDINE DERIVATIVES AS ANTIVIRAL DRUGS AGAINST A FLAVIVIRIDAE, ESPECIALLY HCV 审中-公开
标题翻译：尿苷衍生物作为针对黄病毒科病毒的抗病毒剂; 特别是HCV

公开(公告)号：EP1827457A1

公开(公告)日：2007-09-05

申请号：EP05824567.1

申请日：2005-12-22

申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) Etablissement Public

发明人： AUCAGNE, Vincent , ESCURET, Vanessa , ZOULIM, Fabien , DURANTEL, David , TREPO, Christian , AGROFOGLIO, Luigi , JOUBERT, Nicolas , AMBLARD, Franck

IPC分类号： A61K31/70 , A61P31/12

CPC分类号： A61K31/70

摘要： The invention relates to the use of an uridine derivative of formula (I) : wherein - R1 represents monohalogenated alkynyl or dihalogenated alkenyl; - R2 is chosen from among hydrogen, hydroxyl, O-alkyl, O-CO alkyl and halogen; - R3 is chosen from among hydrogen, hydroxyl, O-alkyl, O-CO alkyl, halogen, SH, S-alkyl and N3; and - R4 is chosen from among hydroxyl, O-alkyl, O-CO alkyl, O-phosphate, O-diphosphate, O-triphosphate and O phosphonate, as well as its possible tautomers, its possible pharmaceutically acceptable addition salts with an acid or a base, and its N-oxide forms, for the preparation of a drug having antiviral activity against a Flaviviridae.

4.

发明公开
METHODS FOR TREATING HEPATITIS B VIRUS (HBV) INFECTION 审中-公开

公开(公告)号：EP3773575A1

公开(公告)日：2021-02-17

申请号：EP18782681.3

申请日：2018-09-27

申请人： INSERM (Institut National de la Santé et de la Recherche Médicale) , Université Claude Bernard Lyon 1 , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS- , Centre Leon Berard , University Of British Columbia , Socpra Sciences Sante et Humaine S E C

发明人： SALVETTI, Anna , DURANTEL, David , CHABROLLES, Hélène , LAHLALI, Tomas , GRIERSON, David , CHABOT, Benoit

IPC分类号： A61K31/4439 , A61P31/20

5.

发明公开
STRONG POTENTIATION OF TLR3 AGONISTS EFFECTS USING FXR AGONISTS AS A COMBINED TREATMENT 审中-公开

公开(公告)号：EP4329761A1

公开(公告)日：2024-03-06

申请号：EP22725888.6

申请日：2022-04-28

申请人： ENYO Pharma

发明人： DARTEIL, Raphaël , DURANTEL, David

IPC分类号： A61K31/496 , A61K31/713 , A61K45/06 , A61P1/04 , A61P19/02 , A61P31/12 , A61P31/14 , A61P35/00 , A61P35/02 , A61P37/00