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    PROSTHETIC HEART VALVE
    3.
    发明公开
    PROSTHETIC HEART VALVE 审中-公开

    公开(公告)号：EP4215161A1

    公开(公告)日：2023-07-26

    申请号：EP22215814.9

    申请日：2016-07-14

    申请人： Edwards Lifesciences Corporation

    发明人： NGUYEN-THIEN-NHON, Diana ,  GEISER, Timothy A. ,  WOOD, Larry ,  SIRIMANNE, Dinesh L. ,  NGUYEN, Son V. ,  LEVI, Tamir S. ,  GUROVICH, Nikolay ,  BUKIN, Michael

    IPC分类号： A61F2/24

    摘要： An implantable prosthetic valve can comprise an annular frame comprising an inflow end and an outflow end and being radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration, the frame defining an axial direction extending from the inflow end to the outflow end, a leaflet structure positioned within the frame and secured thereto, and an annular outer skirt positioned around an outer surface of the frame, wherein the outer skirt comprises an inflow edge secured to the frame at a first location, an outflow edge comprising a plurality of alternating projections and notches, wherein the projections are secured to the frame at a second location, and the notches are not directly secured to the frame, an intermediate portion between the inflow edge and the outflow edge that comprises a plurality of openings.

    PROSTHETIC HEART VALVE HAVING IMPROVED COMMISSURE SUPPORTS
    6.
    发明公开
    PROSTHETIC HEART VALVE HAVING IMPROVED COMMISSURE SUPPORTS 审中-公开

    公开(公告)号：EP4049625A1

    公开(公告)日：2022-08-31

    申请号：EP22167523.4

    申请日：2012-12-07

    申请人： Edwards Lifesciences Corporation

    发明人： YOHANAN, Ziv ,  LEVI, Tamir S. ,  BENICHOU, Netanel ,  BUKIN, Michael ,  GUROVICH, Nikolay ,  SHERMAN, Elena

    IPC分类号： A61F2/24

    摘要： A prosthetic heart valve according to the present disclosure comprises a radially collapsible and expandable annular frame (400) and a leaflet structure comprising a plurality of leaflets mounted within the frame. The frame in particular embodiments can have commissure attachment portions (322) that are configured to support the commissures of the leaflets at locations spaced radially inwardly toward the longitudinal flow axis of the prosthetic valve relative to the frame portions circumscribing the moveable portions of the leaflets. When the leaflets open under pressure of blood flowing through the prosthetic valve, the moveable portions of the leaflets are retained at positions spaced inwardly from the inner surface of the frame to protect against abrasion of the leaflets.

    PROSTHETIC HEART VALVE
    7.
    发明公开
    PROSTHETIC HEART VALVE 审中-公开

    公开(公告)号：EP3865094A1

    公开(公告)日：2021-08-18

    申请号：EP20203764.4

    申请日：2017-08-01

    申请人： Edwards Lifesciences Corporation

    发明人： GUROVICH, Nikolay ,  BUKIN, Michael ,  SHERMAN, Elena ,  LEVI, Tamir S. ,  YOHANAN, Ziv ,  SENESH, Gil ,  KERSH, Dikla ,  TSYPENYUK, Alexey M. ,  CHU, Waina Michelle ,  BARASH, Alexander

    IPC分类号： A61F2/24

    摘要： A prosthetic heart valve can include a radially collapsible and expandable annular frame having a plurality of struts defining openings. The prosthetic heart valve can further include a plurality of leaflets that regulate the flow of blood through the frame. The prosthetic heart valve can also include a sealing member mounted on the frame and having an inner layer and an outer layer. At least the outer layer is mounted on the outside of the frame, and the inner layer covers at least the openings in the frame between adjacent cusp portions of adjacent leaflets and the inner layer does not cover one or more openings in the frame at locations facing the outflow surfaces of the leaflets to permit retrograde blood to flow through the one or more uncovered openings in the frame and into space between the outer layer and the frame.