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1.发明授权
公开(公告)号：EP2967922B1
公开(公告)日：2017-12-20
申请号：EP14779128.9
申请日：2014-03-07
发明人： PHUNG, Andrew , YAMBAO, August R. , KALAM, Faisal , BRUNNETT, William C. , PINTOR, Rafael , SCOTT, Michael, J.
CPC分类号： A61F2/2433 , A61F2/2418
摘要： A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve may include a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A system and method for deployment includes an integrated handle shaft and balloon catheter. A safety member disposed between the balloon catheter and handle shaft prevents premature catheter advancement prior to heart valve placement at the annulus, and also may prevent premature balloon inflation prior to full catheter advancement.
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公开(公告)号：EP1051210A2
公开(公告)日：2000-11-15
申请号：EP99904351.6
申请日：1999-01-28
IPC分类号： A61L33/00
CPC分类号： A61L33/0017
摘要： Enhanced biocompatibility coatings for medical implants and acute exposure medical devices are disclosed in conjunction with methods for their production and use. The biocompatible coatings are particularly advantageous when used in conjunction with high surface area materials such as porous resins, fabrics and textiles and comprise ionically bound complexes of at least one anticlotting compound and at least one quaternary ammonium compound having greater than 0.15 and less than 40 IU of anticlotting compound per CM2. The coatings are produced by forming a solution of the complex having a concentration greater than 0.005 % and less than 1.5 % w/v which is applied to the surface and allowed to dry. The coatings reduce the propensity for thrombus deposition without impairing healing and tissue ingrowth into the device.
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公开(公告)号：EP2967869B1
公开(公告)日：2018-01-31
申请号：EP14778970.5
申请日：2014-03-11
发明人： PINTOR, Rafael , SCOTT, Michael, J. , ZENG, Qinggang , KIM, Grace, M. , CHUNG, Visith , CAMPBELL, Louis, A. , LIN, David, S. , NORASING, Peng , TA, Edwin, T.
CPC分类号： A61F2/2427 , A61F2/2409 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2220/0075 , A61F2230/0067 , A61F2250/0026 , A61F2250/006 , A61F2250/0069
摘要： A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable stent frame, thereby enabling attachment to the annulus without sutures. The prosthetic valve may be a commercially available valve with a sewing ring and the stent frame attached thereto. The stent frame may expand from a conical deployment shape to a conical expanded shape, and may have a cloth covering its entirety as well as a plush sealing flange around its periphery to prevent paravalvular leaking.
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公开(公告)号：EP2613738A2
公开(公告)日：2013-07-17
申请号：EP11823932.6
申请日：2011-08-12
发明人： PINTOR, Rafael , SCOTT, Michael, J. , CHIEN, Thomas , CHEN, Harvey, H. , YAMBAO, August, R. , FARHAT, Lawrence, J. , PHUNG, Andrew , BRUNNETT, William, C. , CRISTEA, Carey , WALLS, Sara M. , ZENQ, Qinggang , ZHENG, Kevin, W. , KALAM, Faisal
摘要： A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the frame attached thereto. The frame may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes an integrated handle shaft and balloon catheter. A valve holder is stored with the heart valve and the handle shaft easily attaches thereto to improve valve preparation steps.
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公开(公告)号：EP2613738B8
公开(公告)日：2019-12-18
申请号：EP11823932.6
申请日：2011-08-12
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公开(公告)号：EP1429690A1
公开(公告)日：2004-06-23
申请号：EP01973534.9
申请日：2001-09-26
IPC分类号： A61F2/24
CPC分类号： A61F2/2409
摘要： A sewing ring for prosthetic heart valves that is connected and configured to pivot outward. A biocompatible fabric covering surrounds at least a portion of the sewing ring, and the ring may be exclusively connected to a stent with the fabric. The sewing ring may be generally planar and of uniform thickness, or may be of varying thickness. The fabric may be used to encompass both the stent and the sewing ring, and may be a single piece. A seam may be provided in the fabric as a discrete pivoting line. The sewing ring may be convertible between bi-stable positions. The ring may extend outward in a frusto-conical shape so as to enable inversion between a position facing the inflow end of the valve and a position facing the outflow end of the valve. The sewing ring may have a compliant insert having a celled construction defined by outer walls and inner ribs. A method of implantation, and a method of assembly of the heart valve is also provided.
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7.发明公开SYSTEMS AND METHODS FOR ENSURING SAFE AND RAPID DEPLOYMENT OF PROSTHETIC HEART VALVES 有权系统和方法，以确保人工心脏瓣膜的安全和快速释放
公开(公告)号：EP2967922A1
公开(公告)日：2016-01-20
申请号：EP14779128.9
申请日：2014-03-07
发明人： PHUNG, Andrew , YAMBAO, August R. , KALAM, Faisal , BRUNNETT, William C. , PINTOR, Rafael , SCOTT, Michael, J.
CPC分类号： A61F2/2433 , A61F2/2418
摘要： A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve may include a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A system and method for deployment includes an integrated handle shaft and balloon catheter. A safety member disposed between the balloon catheter and handle shaft prevents premature catheter advancement prior to heart valve placement at the annulus, and also may prevent premature balloon inflation prior to full catheter advancement.
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公开(公告)号：EP2967869A1
公开(公告)日：2016-01-20
申请号：EP14778970.5
申请日：2014-03-11
发明人： PINTOR, Rafael , SCOTT, Michael, J. , ZENG, Qinggang , KIM, Grace, M. , CHUNG, Visith , CAMPBELL, Louis, A. , LIN, David, S. , NORASING, Peng , TA, Edwin, T.
CPC分类号： A61F2/2427 , A61F2/2409 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2220/0075 , A61F2230/0067 , A61F2250/0026 , A61F2250/006 , A61F2250/0069
摘要： A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable stent frame, thereby enabling attachment to the annulus without sutures. The prosthetic valve may be a commercially available valve with a sewing ring and the stent frame attached thereto. The stent frame may expand from a conical deployment shape to a conical expanded shape, and may have a cloth covering its entirety as well as a plush sealing flange around its periphery to prevent paravalvular leaking.
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公开(公告)号：EP1429690B1
公开(公告)日：2006-11-29
申请号：EP01973534.9
申请日：2001-09-26
IPC分类号： A61F2/24
CPC分类号： A61F2/2409
摘要： A sewing ring for prosthetic heart valves that is connected and configured to pivot outward. A biocompatible fabric covering surrounds at least a portion of the sewing ring, and the ring may be exclusively connected to a stent with the fabric. The sewing ring may be generally planar and of uniform thickness, or may be of varying thickness. The fabric may be used to encompass both the stent and the sewing ring, and may be a single piece. A seam may be provided in the fabric as a discrete pivoting line. The sewing ring may be convertible between bi-stable positions. The ring may extend outward in a frusto-conical shape so as to enable inversion between a position facing the inflow end of the valve and a position facing the outflow end of the valve. The sewing ring may have a compliant insert having a celled construction defined by outer walls and inner ribs. A method of implantation, and a method of assembly of the heart valve is also provided.
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