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公开(公告)号：EP4233790A2
公开(公告)日：2023-08-30
申请号：EP23169994.3
申请日：2014-11-21
发明人： KARAPETIAN, Emil , STANISLAUS, Maria Charles Vija , BAK-BOYCHUK, Gregory , OLSON, Christopher J. , HERNANDEZ, Cristobal R. , BRUNNETT, William C. , BENICHOU, Netanel , FRESCHAUF, Lauren R. , SIEGEL, Alexander J.
IPC分类号： A61F2/07
摘要： This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises an annular main body formed by a plurality of angled struts, the main body including a plurality of peaks formed by the intersection of respective adjacent struts. The support frame further comprises one or more leaflet-engaging mechanisms configured to engage leaflets of the heart valve. The support frame can be radially expandable and collapsible.
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2.发明公开SYSTEMS AND METHODS FOR ENSURING SAFE AND RAPID DEPLOYMENT OF PROSTHETIC HEART VALVES 有权系统和方法，以确保人工心脏瓣膜的安全和快速释放
公开(公告)号：EP2967922A1
公开(公告)日：2016-01-20
申请号：EP14779128.9
申请日：2014-03-07
发明人： PHUNG, Andrew , YAMBAO, August R. , KALAM, Faisal , BRUNNETT, William C. , PINTOR, Rafael , SCOTT, Michael, J.
CPC分类号： A61F2/2433 , A61F2/2418
摘要： A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve may include a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A system and method for deployment includes an integrated handle shaft and balloon catheter. A safety member disposed between the balloon catheter and handle shaft prevents premature catheter advancement prior to heart valve placement at the annulus, and also may prevent premature balloon inflation prior to full catheter advancement.
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公开(公告)号：EP3332741A1
公开(公告)日：2018-06-13
申请号：EP17210798.9
申请日：2011-08-12
发明人： PINTOR, Rafael , SCOTT, Michael J. , CHIEN, Thomas , CHEN, Harvey H. , YAMBAO, August R. , FARHAT, Lawrence J. , PHUNG, Andrew , BRUNNETT, William C. , CRISTEA, Carey , WALLS, Sara M. , ZENQ, Qinggang , ZHENG, Kevin W. , KALAM, Faisal
CPC分类号： A61F2/2433 , A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2220/0008 , A61F2220/0016 , A61F2220/0025 , A61F2220/005 , A61F2220/0075 , A61F2220/0083 , A61F2230/0067 , A61F2250/0018 , A61F2250/0039 , A61F2250/0048 , A61F2250/006
摘要： A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the frame attached thereto. The frame may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes an integrated handle shaft and balloon catheter. A valve holder is stored with the heart valve and the handle shaft easily attaches thereto to improve valve preparation steps.
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公开(公告)号：EP3527172A1
公开(公告)日：2019-08-21
申请号：EP19161374.4
申请日：2014-11-21
发明人： KARAPETIAN, Emil , STANISLAUS, Maria Charles Vija , BAK-BOYCHUK, Gregory , OLSON, Christopher J. , HERNANDEZ, Cristobal R. , BRUNNETT, William C. , BENICHOU, Netanel , FRESCHAUF, Lauren R. , SIEGEL, Alexander J.
摘要： This application relates to apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency.
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公开(公告)号：EP4233790A3
公开(公告)日：2023-10-11
申请号：EP23169994.3
申请日：2014-11-21
发明人： KARAPETIAN, Emil , STANISLAUS, Maria Charles Vija , BAK-BOYCHUK, Gregory , OLSON, Christopher J. , HERNANDEZ, Cristobal R. , BRUNNETT, William C. , BENICHOU, Netanel , FRESCHAUF, Lauren R. , SIEGEL, Alexander J.
摘要： This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises an annular main body formed by a plurality of angled struts, the main body including a plurality of peaks formed by the intersection of respective adjacent struts. The support frame further comprises one or more leaflet-engaging mechanisms configured to engage leaflets of the heart valve. The support frame can be radially expandable and collapsible.
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7.发明授权
公开(公告)号：EP2967922B1
公开(公告)日：2017-12-20
申请号：EP14779128.9
申请日：2014-03-07
发明人： PHUNG, Andrew , YAMBAO, August R. , KALAM, Faisal , BRUNNETT, William C. , PINTOR, Rafael , SCOTT, Michael, J.
CPC分类号： A61F2/2433 , A61F2/2418
摘要： A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve may include a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A system and method for deployment includes an integrated handle shaft and balloon catheter. A safety member disposed between the balloon catheter and handle shaft prevents premature catheter advancement prior to heart valve placement at the annulus, and also may prevent premature balloon inflation prior to full catheter advancement.
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公开(公告)号：EP2922592A1
公开(公告)日：2015-09-30
申请号：EP13856071.9
申请日：2013-11-20
发明人： BRUNNETT, William C. , STANISLAUS, Charles , RABITO, Glen T. , ARMER, Dustin P. , KARAPETIAN, Emil , KHUU, Nancy
IPC分类号： A61M25/088 , A61F2/24
CPC分类号： A61F2/2445 , A61F2/2412 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2466 , A61F2230/0069 , A61F2250/0063
摘要： According to one representative embodiment, a method of treating aortic insufficiency comprises delivering a support structure to a position around the leaflets of a native heart valve. The support structure comprises an annular body defining an interior and at least one projection extending radially inwardly from the annular body. An expandable prosthetic heart valve can be advanced into the native heart valve and into the interior of the annular body. The prosthetic heart valve can be expanded into contact with the leaflets of the native valve, thereby causing the leaflets of the native valve to be frictionally secured between an inner surface of the annular body and an outer surface of the prosthetic heart valve and causing the at least one projection and a portion of one of the leaflets contacted by the at least one projection to extend into an opening of the frame of the prosthetic valve.
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