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    METHOD FOR MEASUREMENT OF EQUOL IN BIOLOGICAL SAMPLE BY IMMUNOASSAY, KIT FOR THE MEASUREMENT, AND METHOD FOR DETERMINATION OF EQUOL PRODUCTION ABILITY OF SUBJECT
    1.
    发明公开
    METHOD FOR MEASUREMENT OF EQUOL IN BIOLOGICAL SAMPLE BY IMMUNOASSAY, KIT FOR THE MEASUREMENT, AND METHOD FOR DETERMINATION OF EQUOL PRODUCTION ABILITY OF SUBJECT 有权
    方法在生物样品利用一个免疫检测，KIT为确定EQUOLHERSTELLUNGSKAPAZITÄT一个人测量和测量方法测EQUOLGEHALTS的

    公开(公告)号：EP2431740A1

    公开(公告)日：2012-03-21

    申请号：EP10774917.8

    申请日：2010-05-11

    申请人： Eiken Kagaku Kabushiki Kaisha ,  Otsuka Pharmaceutical Co., Ltd.

    发明人： MINEKAWA,Takayuki ,  SHINDOME, Kumiko ,  ABE, Katsushi ,  OKUMA, Hiroshi ,  ANDO, Chieko ,  ABIRU, Yasuhiro

    IPC分类号： G01N33/53

    CPC分类号： G01N33/5308 ,  C07K16/44

    摘要： An object of the present invention is to provide a method for measuring equal in a biological sample by an immunological method, a kit for the measurement, and a method for determining equol-producing ability of a subject.
    The measurement method of the present invention is characterized in that S-equol is used as at least one antigen selected from the group consisting of a standard antigen used for the preparation of a standard curve and a labeled antigen that competes with equol in a biological sample. The kit of the present invention is characterized in including S-equol as at least one antigen selected from the group consisting of the standard antigen and the labeled antigen. The determination method of the present invention includes steps of measuring equal in a biological sample derived from a subject who has ingested soybean isoflavane by an immunological method using S-equol as at least one antigen selected from the group consisting of the standard antigen and the labeled antigen, and determining an equol-producing ability of the subject based on the measured value of equol obtained in the above step.

    摘要翻译： 本发明的一个目的是提供一种用于在免疫学方法测量相等的生物样品中通过提供一种方法，用于测量的试剂盒，以及用于受试者的确定性采矿雌马酚产生能力的方法。 本发明的测定方法中也S-雌马酚被用作选自用于标准曲线的制备和标记抗原的标准抗原中的至少一种抗原与雌马酚做竞争的生物样品中的特征 ， 本发明的试剂盒中，包括S-牛尿酚的特征为选自以下的标准抗原和标记的抗原中的至少一种抗原。 本发明的测定方法包括使用S-牛尿酚测量从谁已经通过免疫学方法摄取大豆isoflavanes的受试者的生物样品中的相等的步骤选自下组的标准抗原和标记的选择的至少一种抗原 抗原，以及基于在上述工序中得到的雌马酚的测量值的受试者的雌马酚产生能力的确定性挖掘。