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公开(公告)号：EP2937337A1
公开(公告)日：2015-10-28
申请号：EP13865671.5
申请日：2013-12-19
IPC分类号： C07D215/48 , A61K9/19 , A61K31/47 , A61P35/00 , A61P35/04
CPC分类号： C07D215/48 , C07B2200/13
摘要： The invention provides an amorphous form of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide.
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2.发明授权CRYSTAL OF SALT OF 4-(3-CHLORO-4-(CYCLOPROPYLAMINOCARBONYL)AMINO-PHENOXY)-7-METHOXY-6-QUINOLINECARBOXAMIDE OR OF SOLVATE THEREOF AND PROCESSES FOR PRODUCING THESE 有权水晶盐4-（3-氯-4-（环丙基）氨基苯氧基）-7-甲氧基-6-氨甲酰喹啉或FOR它们的溶剂合物和方法及其
公开(公告)号：EP1698623B1
公开(公告)日：2015-04-15
申请号：EP04807580.8
申请日：2004-12-22
发明人： MATSUSHIMA, Tomohiro , NAKAMURA, Taiju , YOSHIZAWA, Kazuhiro c/o Eisai Co., Ltd. , KAMADA, Atsushi , AYATA, Yusuke c/o Eisai Co., Ltd, , SUZUKI, Naoko , ARIMOTO, Itaru, c/o Eisai Co.,Ltd , SAKAGUCHI, Takahisa , GOTODA, Masaharu
IPC分类号： C07D215/48 , A61K31/47 , A61P9/10 , A61P17/06 , A61P27/02 , A61P29/00 , A61P35/00 , A61P43/00
CPC分类号： C07D215/48
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3.发明公开BENZIMIDAZOLE COMPOUND HAVING GASTRIC ACID SECRETION INHIBITORY ACTIVITY 审中-公开BENZIMIDAZOLVERBINDUNG MITMAGENSÄURE-SEKRETION VERHINDERNDERAKTIVITÄT
公开(公告)号：EP2065379A1
公开(公告)日：2009-06-03
申请号：EP07829601.9
申请日：2007-10-11
IPC分类号： C07D401/12 , A61K31/4439 , A61K31/549 , A61P1/04 , A61P31/04 , A61P43/00 , C07D405/14 , C07D493/10 , C07D513/14 , C07D519/00
CPC分类号： C07D401/12 , C07D405/14 , C07D493/10 , C07D513/14 , C07D519/00
摘要： The present invention provides a compound that has superior gastric acid secretion inhibitory action, ample long-lasting gastric acid secretion inhibitory action, and is able to maintain intragastric pH at a high level for an extended period of time, making it useful as a therapeutic or prophylactic agent for diseases or symptoms caused by gastric acid, as well as an active form of this compound (form to which the compound is converted in the body following administration thereof) in the form of a compound represented by general formula (1 a) (wherein R2 represents a group represented by formula (I) or the like, and R1, R3, W1 and X - are as defined in the description).
摘要翻译： 本发明提供了具有优良的胃酸分泌抑制作用，充足的持久胃酸分泌抑制作用的化合物，能够将胃内pH保持在高水平长时间，使其成为治疗性或 由胃酸引起的疾病或症状的预防剂以及该化合物的活性形式（化合物在给药后在体内转化的形式）以通式（1a）表示的化合物的形式（ 其中R 2表示由式（I）等表示的基团，R 1，R 3，W 1和X - 如说明书中所定义）。
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