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公开(公告)号：EP2139558A1
公开(公告)日：2010-01-06
申请号：EP07724332.7
申请日：2007-04-18
申请人： Elekta AB (PUBL)
发明人： BROWN, Kevin, John
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61N5/103 , A61N5/1067 , A61N5/1084 , A61N2005/1061
摘要： A treatment planning apparatus for radiation treatment is described, adapted to accept a treatment plan comprising (i) a prior image of a region to be treated and a plurality of dose locations within the prior image, and (ii) a current image of the region to be treated, the apparatus comprising an associating means arranged, for each dose location, to locate an anatomical structure in the prior image proximate that dose location; a comparator for comparing the prior image and the current image, locating in the current image at least those anatomical structures that are associated with a dose location, and determining a transformation between the prior image and the current image for each anatomical structure; and a processing means for determining a current dose location by applying to each dose location the transformation determined in respect of the associated anatomical structure. This is particularly useful for the neck region of a patient, where the likelihood and magnitude of movements are both high, but there are plenty of distinguishable anatomical features in the form of the vertebrae.
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公开(公告)号：EP1364375B1
公开(公告)日：2014-04-09
申请号：EP02702483.5
申请日：2002-02-27
申请人： Elekta AB (publ)
IPC分类号： G21K1/04
CPC分类号： A61N5/1042 , A61N5/1047 , G21K1/04 , G21K1/046
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公开(公告)号：EP2229805B1
公开(公告)日：2011-10-12
申请号：EP07857056.1
申请日：2007-12-21
发明人： BROWN, Kevin, John , THOMPSON, Maria, Giulia , ROBERTS, David, Anthony , EVANS, Philip, Mark , HANSEN, Vibeke, Nordmark
IPC分类号： H05H9/04
CPC分类号： H05H7/12 , H01J35/00 , H01J2235/08 , H05H6/00 , H05H9/04
摘要： X-ray apparatus comprises a linear accelerator adapted to produce a beam of electrons at one of at least two selectable energies and being controlled to change the selected energy on a periodic basis, and a target to which the beam is directed thereby to produce a beam of x-radiation, the target being non- homogenous and being driven to move periodically in synchrony with the change of the selected energy. In this way, the target can move so that a different part is exposed to the electron beam when different pulses arrive. This enables the appropriate target material to be employed depending on the selected energy. The easiest form of periodic movement for the target is likely to be a rotational movement. The target can be immersed in a coolant fluid such as water. The linear accelerator can be of the type disclosed in WO2006/097697A1. The target preferably contains at least one exposed area of tungsten and/or at least one exposed area of carbon. These can be present as inhomogeneities in the material of which the target is composed, such as Carbon inserts in a Tungsten substrate (or vice versa), alternating segments of Carbon and Tungsten, Carbon and Tungsten inserts in a substrate of a third material, or arrangements involving other materials in addition to or instead of Carbon and/or Tungsten. Alternatively, the target can be of a homogenous material but have inhomogeneities in its thickness to cater for the different electron energies. The same concept can be applied to the filter. A detector can be provided, operating in synchrony with the energy variation. Such an x-ray apparatus can form a part of a radiotherapy apparatus, in which case the first selected energy can be a diagnostic energy and a second selected energy a therapeutic energy.
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公开(公告)号：EP2229805A1
公开(公告)日：2010-09-22
申请号：EP07857056.1
申请日：2007-12-21
发明人： BROWN, Kevin, John , THOMPSON, Maria, Giulia , ROBERTS, David, Anthony , EVANS, Philip, Mark , HANSEN, Vibeke, Nordmark
IPC分类号： H05H9/04
CPC分类号： H05H7/12 , H01J35/00 , H01J2235/08 , H05H6/00 , H05H9/04
摘要： X-ray apparatus comprises a linear accelerator adapted to produce a beam of electrons at one of at least two selectable energies and being controlled to change the selected energy on a periodic basis, and a target to which the beam is directed thereby to produce a beam of x-radiation, the target being non- homogenous and being driven to move periodically in synchrony with the change of the selected energy. In this way, the target can move so that a different part is exposed to the electron beam when different pulses arrive. This enables the appropriate target material to be employed depending on the selected energy. The easiest form of periodic movement for the target is likely to be a rotational movement. The target can be immersed in a coolant fluid such as water. The linear accelerator can be of the type disclosed in WO2006/097697A1. The target preferably contains at least one exposed area of tungsten and/or at least one exposed area of carbon. These can be present as inhomogeneities in the material of which the target is composed, such as Carbon inserts in a Tungsten substrate (or vice versa), alternating segments of Carbon and Tungsten, Carbon and Tungsten inserts in a substrate of a third material, or arrangements involving other materials in addition to or instead of Carbon and/or Tungsten. Alternatively, the target can be of a homogenous material but have inhomogeneities in its thickness to cater for the different electron energies. The same concept can be applied to the filter. A detector can be provided, operating in synchrony with the energy variation. Such an x-ray apparatus can form a part of a radiotherapy apparatus, in which case the first selected energy can be a diagnostic energy and a second selected energy a therapeutic energy.
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公开(公告)号：EP1325503A1
公开(公告)日：2003-07-09
申请号：EP01967515.6
申请日：2001-09-19
申请人： Elekta AB (publ)
IPC分类号： G21K1/04
CPC分类号： G21K1/046 , A61N5/1042 , A61N5/1045 , A61N2005/1095 , G21K1/04
摘要： A collimator set for a radiotherapy apparatus comprises, in sequence, an aperture collimator, a multi-leaf collimator with a pair of opposing arrays of elongate leaves each moveable longitudinally in a Y direction, and a leaf edge collimator, the aperture collimator being adapted to collimate the beam in the X and Y direction to a first extent, and the leaf edge collimator being adapted to further collimate the extent of the beam in the Y direction to a second and therefore lesser extend. This means that to close a pair of opposing leaves, they are moved to their minimum separation, with the gap being convered by the leaf edge collimator. The MLC is after the aperture collimator, so in combination with thin leaves, the MLC leaves will project a much reduced leaf width at the isocentre of the radiotherapy apparatus and collimation of the radiation field by fractional leaf widths becomes unnecessary. A radiotherapy apparatus comprising a collimator set as defined above is also disclosed.
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公开(公告)号：EP1589876B1
公开(公告)日：2011-10-19
申请号：EP04703444.2
申请日：2004-01-20
申请人： Elekta AB (publ)
发明人： BROWN, Kevin, John , JAFFRAY, David , SIEWERDSEN, Jeffrey , VAN HERK, Marcel , SONKE, Jan-Jakob
CPC分类号： A61B6/541 , A61B6/032 , G06T11/005 , G06T2211/412
摘要： Artefacts in the reconstructed volume data of cone beam CT systems can be removed by the application of respiration correlation techniques to the acquired projection images. To achieve this, the phase of the patients breathing is monitored while acquiring projection images continuously. On completion of the acquisition, projection images that have comparable breathing phases can be selected from the complete set, and these are used to reconstruct the volume data using similar techniques to those of conventional CT. Any phase can be selected and therefore the effect of breathing can be studied. It is also possible to use a feature in the projection image(s) such as the patient's diaphragm to determine the breathing phase. This feature in the projection images can be used to control delivery of therapeutic radiation dependent on the patient's breathing cycle, to ensure that the tumour is in the correct position when the radiation is delivered.
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公开(公告)号：EP1589876A1
公开(公告)日：2005-11-02
申请号：EP04703444.2
申请日：2004-01-20
申请人： Elekta AB (publ)
发明人： BROWN, Kevin, John , JAFFRAY, David , SIEWERDSEN, Jeffrey , VAN HERK, Marcel , SONKE, Jan-Jakob
CPC分类号： A61B6/541 , A61B6/032 , G06T11/005 , G06T2211/412
摘要： Artefacts in the reconstructed volume data of cone beam CT systems can be removed by the application of respiration correlation techniques to the acquired projection images. To achieve this, the phase of the patients breathing is monitored while acquiring projection images continuously. On completion of the acquisition, projection images that have comparable breathing phases can be selected from the complete set, and these are used to reconstruct the volume data using similar techniques to those of conventional CT. Any phase can be selected and therefore the effect of breathing can be studied. It is also possible to use a feature in the projection image(s) such as the patient's diaphragm to determine the breathing phase. This feature in the projection images can be used to control delivery of therapeutic radiation dependent on the patient's breathing cycle, to ensure that the tumour is in the correct position when the radiation is delivered.
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公开(公告)号：EP2326390B1
公开(公告)日：2013-12-11
申请号：EP09784773.5
申请日：2009-07-24
申请人： Elekta AB (publ)
IPC分类号： A61N5/10
CPC分类号： A61N5/1084 , A61N5/1065 , A61N2005/1059 , A61N2005/1061 , A61N2005/1063 , A61N2005/1097
摘要： A highly compact, high-performance volumetric imaging system is proposed, that is integrated with a multi-source Cobalt-60 gamma irradiator for high throughput, high accuracy and minimally invasive fractioned treatments of intracranial, orbital and head-and-neck targets.
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公开(公告)号：EP2326390A1
公开(公告)日：2011-06-01
申请号：EP09784773.5
申请日：2009-07-24
申请人： Elekta AB (publ)
IPC分类号： A61N5/10
CPC分类号： A61N5/1084 , A61N5/1065 , A61N2005/1059 , A61N2005/1061 , A61N2005/1063 , A61N2005/1097
摘要： A highly compact, high-performance volumetric imaging system is proposed, that is integrated with a multi-source Cobalt-60 gamma irradiator for high throughput, high accuracy and minimally invasive fractioned treatments of intracranial, orbital and head-and-neck targets.
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公开(公告)号：EP1680023B1
公开(公告)日：2008-08-27
申请号：EP04768991.4
申请日：2004-10-22
申请人： Elekta AB (publ)
发明人： BROWN, Kevin, John
CPC分类号： A61N5/1081 , A61N5/10 , A61N5/1042 , A61N5/1082
摘要： A radiation therapy/surgery device optimised to meet the needs of the Neurosurgeon is provided, i.e. one for the treatment of tumours in the brain. It combines the qualities of a good penumbra and accuracy, simple prescription and operation, together with high reliability and minimal technical support. The device comprises a rotateable support, on which is provided a mount extending from the support out of the plane of the circle, and a radiation source attached to the mount via a pivot, the pivot having an axis which passes through the axis of rotation of the support, the radiation source being aligned so as to produce a beam which passes through the co-incidence of the rotation axis and the pivot. It will generally be easier to engineer the apparatus if the rotateable support is planar, and more convenient if the rotateable support is disposed in an upright position. The rotation of the rotateable support will be eased if this part of the apparatus is circular. A particularly preferred orientation is one in which the radiation source is spaced from the rotateable support, to allow it to pivot without fouling the latter. It is thus preferred that the mount extends transverse to the support. In this way, the pivot axis is spaced from the rotateable support providing free space in which the radiation source can pivot. Another way of expressing this preference is to state that the pivot axis is located out of the plane of the rotateable support. To simplify the geometry of the device and the associated arithmetic, it is preferred both that the pivot axis is substantially perpendicular to the rotation axis, and that the beam direction is perpendicular to the pivot axis. It is preferred that the radiation source is a linear accelerator. The output of the radiation source is preferably collimated to conform to the shape of the area to be treated.
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