公开(公告)号：EP2970254A1

公开(公告)日：2016-01-20

申请号：EP14712894.6

申请日：2014-03-04

Applicant: Eli Lilly and Company

Inventor： JONES, Spencer Brian ,  NORMAN, Bryan Hurst ,  PFEIFER, Lance Allen

IPC: C07D471/02 ,  C07D487/02 ,  C07D491/02

CPC classification number: C07D519/00 ,  C07D471/02 ,  C07D487/02 ,  C07D491/02

Abstract: The present invention provides compounds of the formula I, wherein X is a bond or CH
2 ; Q is CH
2 or O; L is selected from the group consisting of -OCH
2 - and -CH
2 O-; or a pharmaceutically acceptable salt thereof. Compounds of the invention are autotaxin inhibitors.

公开(公告)号：EP4352053A1

公开(公告)日：2024-04-17

申请号：EP22741885.2

申请日：2022-06-08

Applicant: Eli Lilly and Company

Inventor： BARDA, David Anthony ,  CLAYTON, Joshua Ryan ,  FRANCISKOVICH, Jeffry Bernard ,  FURNESS, Kelly Wayne ,  GERNERT, Douglas Linn ,  HENRY, James Robert ,  JOHNSTON, Richard Duane ,  JONES, Spencer Brian ,  LAMAR, Jason Eric ,  LEVINSON, Adam Marc ,  MBOFANA, Curren Tapfuma ,  RODRIGUEZ, Michael John ,  RUBIO, Almudena ,  SI, Chong ,  ZHAO, Gaiying ,  ZIA-EBRAHIMI, Mohammed Sadegh

IPC: C07D409/14 ,  A61P35/00 ,  C07D409/04 ,  C07D487/04 ,  C07D487/08 ,  C07D498/08 ,  C07D519/00 ,  A61K31/517

CPC classification number: C07D498/08 ,  C07D487/08 ,  C07D519/00 ,  C07D409/14 ,  C07D487/04 ,  C07D409/04 ,  A61P35/00

公开(公告)号：EP3908585A1

公开(公告)日：2021-11-17

申请号：EP20703322.6

申请日：2020-01-03

Applicant: ELI LILLY AND COMPANY

Inventor： COATES, David Andrew ,  FRIMPONG, Kwame ,  HOLLOWAY, William Glen ,  JONES, Spencer Brian ,  LEVINSON, Adam Marc ,  LUGAR, Charles Willis III ,  RICHETT, Michael Enrico ,  WATSON, Brian Morgan ,  WOODMAN, Michael Edward

IPC: C07D487/04 ,  A61K31/5025 ,  A61P17/06 ,  A61P37/00