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公开(公告)号：EP1904494B1
公开(公告)日：2010-12-01
申请号：EP06735794.7
申请日：2006-02-23
发明人： BARDA, David, Anthony , BURKHOLDER, Timothy, Paul , CLAYTON, Joshua, Ryan , HAO, Yan , HEATH, Perry, Clark , HENRY, James, Robert , KNOBELOCH, John, Monte , MENDEL, David , MCLEAN, Johnathan, Alexander , REMICK, David, Michael , REMPALA, Mark, Edward , WANG, Zhao-Qing , YIP, Yvonne, Yee, Mai , ZHONG, Boyu
IPC分类号： C07D471/04 , A61K31/4375 , A61P35/04
CPC分类号： C07D471/04
摘要： The present invention provides compounds that are inhibitors of VEGF-R2 of the formula: (I) and methods of using these compounds.
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公开(公告)号：EP2491032B1
公开(公告)日：2014-04-16
申请号：EP10774072.2
申请日：2010-10-20
发明人： BEIGHT, Douglas, Wade , BURKHOLDER, Timothy, Paul , CLAYTON, Joshua, Ryan , EGGEN, MariJean , HENRY, Kenneth, James, Junior , JOHNS, Deidre, Michelle , PARTHASARATHY, Saravanan , PEI, Huaxing , REMPALA, Mark, Edward , SAWYER, Jason, Scott
IPC分类号： C07D471/04 , C07D487/04 , A61K31/519 , A61P35/00
CPC分类号： C07D471/04 , A61K31/519 , C07D487/04
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公开(公告)号：EP2491032A1
公开(公告)日：2012-08-29
申请号：EP10774072.2
申请日：2010-10-20
发明人： BEIGHT, Douglas, Wade , BURKHOLDER, Timothy, Paul , CLAYTON, Joshua, Ryan , EGGEN, MariJean , HENRY, Kenneth, James, Junior , JOHNS, Deidre, Michelle , PARTHASARATHY, Saravanan , PEI, Huaxing , REMPALA, Mark, Edward , SAWYER, Jason, Scott
IPC分类号： C07D471/04 , C07D487/04 , A61K31/519 , A61P35/00
CPC分类号： C07D471/04 , A61K31/519 , C07D487/04
摘要： The present invention provides AKT inhibitors of the formula: Formula I The present invention also provides pharmaceutical compositions comprising compounds of Formula I, uses of compounds of Formula I and method of using compounds of Formula I.
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公开(公告)号：EP1904494A1
公开(公告)日：2008-04-02
申请号：EP06735794.7
申请日：2006-02-23
发明人： BARDA, David, Anthony , BURKHOLDER, Timothy, Paul , CLAYTON, Joshua, Ryan , HAO, Yan , HEATH, Perry, Clark , HENRY, James, Robert , KNOBELOCH, John, Monte , MENDEL, David , MCLEAN, Johnathan, Alexander , REMICK, David, Michael , REMPALA, Mark, Edward , WANG, Zhao-Qing , YIP, Yvonne, Yee, Mai , ZHONG, Boyu
IPC分类号： C07D471/04 , A61K31/4375 , A61P35/04
CPC分类号： C07D471/04
摘要： The present invention provides compounds that are inhibitors of VEGF-R2 of the formula: (I) and methods of using these compounds.
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