公开(公告)号：EP1509538A1

公开(公告)日：2005-03-02

申请号：EP03726818.2

申请日：2003-05-13

申请人： Enanta Pharmaceuticals, Inc.

发明人： OR, Yat, Sun ,  WANG, Guoqiang ,  PHAN, Ly, Tam ,  NIU, Deqiang ,  QUI, Yao-Ling ,  VO, Nha, Huu ,  FARMER, Jay, Judson ,  HOU, Ying

IPC分类号： C07H17/00 ,  A61K31/00

CPC分类号： C07H17/08

摘要： The present invention discloses compounds of formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

公开(公告)号：EP1506214A1

公开(公告)日：2005-02-16

申请号：EP03733983.5

申请日：2003-05-09

申请人： Enanta Pharmaceuticals, Inc.

发明人： OR, Yat, Sun ,  WANG, Guoqiang ,  PHAN, Ly, Tam ,  NIU, Deqiang ,  VO, Nha, Huu ,  QIU, Yao-Ling ,  WANG, Yanchun ,  BUSUYEK, Marina ,  HOU, Ying ,  PENG, Yulin ,  KIM, Heejin ,  LIU, Tongzhu ,  FARMER, Jay Judson ,  XU, Guoyou

IPC分类号： C07H17/08 ,  A61K31/7048 ,  A61P31/04

CPC分类号： C07H17/08

摘要： The present invention discloses compounds of formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

公开(公告)号：EP1373289A1

公开(公告)日：2004-01-02

申请号：EP01997162.1

申请日：2001-12-27

申请人： Enanta Pharmaceuticals, Inc.

发明人： OR, Yat, Sun ,  VO, Nha, Huu ,  WANG, Jianchao ,  PHAN, Ly, Tam

IPC分类号： C07H17/08 ,  A61K31/70 ,  A61P31/04

CPC分类号： C07H17/08 ,  A61K31/70

摘要： Novel 9-amino-14-membered macrolides and pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier, a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically- effective amount of a compound of the invention and processes for the preparation of such compounds.