公开(公告)号：EP2931309A1

公开(公告)日：2015-10-21

申请号：EP13811884.9

申请日：2013-12-17

申请人： Eurocine Vaccines AB

发明人： ARWIDSSON, Hans ,  Maltais, Anna-Karin

IPC分类号： A61K39/145

CPC分类号： A61K39/145 ,  A61K39/12 ,  A61K39/39 ,  A61K2039/5252 ,  A61K2039/54 ,  A61K2039/543 ,  A61K2039/545 ,  A61K2039/55511 ,  A61K2039/55566 ,  C12N2760/16134 ,  C12N2760/16234 ,  Y02A50/466

摘要： The present invention relates in a first aspect to a vaccine kit comprising a) a first vaccine component comprising i) a first set of one or more containers, each container containing a vaccine composition for intranasal administration, b) optionally a second vaccine component comprising a second set of one or more containers, each container containing a vaccine composition for intranasal administration, and c) optionally instructions for use, wherein each container of the first and second set of containers contains a volume of the vaccine composition from about 5 microliter to about 400 microliter. The present invention also relates to: An administration regimen for intranasal administration of a vaccine composition for use in immunizing a human. A device for use in administration of vaccine compositions. The use of: a) a first vaccine component comprising i) a first set of one or more containers, each container containing a vaccine composition for intranasal administration, b) optionally a second vaccine component comprising a second set of one or more containers, each container containing a vaccine composition for intranasal administration, wherein each container of the first and second set of containers contains a total volume of the vaccine composition from about 5 microliter to about 400 microliter for immunizing a human. The use of: a) a first vaccine component comprising i) a first set of one or more containers, each container containing a vaccine composition for intranasal administration, b) optionally a second vaccine component comprising a second set of one or more containers, each container containing a vaccine composition for intranasal administration, wherein each container of the first and second set of containers contains a total volume of the vaccine composition from about 5 microliter to about 400 microliter for the preparation of a vaccine for intranasally immunizing a human. The method of treating a person in need of a vaccination. The vaccine formulated for intranasal administering.

摘要翻译： 本发明在第一方面涉及疫苗试剂盒，其包含a）第一疫苗组分，其包含i）第一组一个或多个容器，每个容器含有用于鼻内给药的疫苗组合物，b）任选的第二疫苗组分，其包含 第二组一个或多个容器，每个容器含有用于鼻内给药的疫苗组合物，和c）任选的使用说明书，其中第一组和第二组容器的每个容器含有约5微升至约 400微升。 本发明还涉及：用于鼻内施用用于免疫人的疫苗组合物的给药方案。 用于疫苗组合物施用的装置。 使用：a）第一疫苗组分，其包含i）第一组一个或多个容器，每个容器含有用于鼻内给药的疫苗组合物，b）任选的第二疫苗组分，其包含第二组一个或多个容器，每个容器 含有用于鼻内给药的疫苗组合物的容器，其中第一和第二组容器的每个容器含有用于免疫人的约5微升至约400微升的疫苗组合物的总体积。 使用：a）第一疫苗组分，其包含i）第一组一个或多个容器，每个容器含有用于鼻内给药的疫苗组合物，b）任选的第二疫苗组分，其包含第二组一个或多个容器，每个容器 容器，其含有用于鼻内给药的疫苗组合物，其中第一和第二组容器的每个容器含有约5微升至约400微升的疫苗组合物的总体积，用于制备用于鼻内免疫人的疫苗。 治疗需要接种疫苗的人的方法。 疫苗配制用于鼻内给药。

公开(公告)号：EP2742952A1

公开(公告)日：2014-06-18

申请号：EP12197522.1

申请日：2012-12-17

申请人： Eurocine Vaccines AB

发明人： Arwidsson, Hans ,  Maltais, Anna-Karin

IPC分类号： A61K39/145 ,  A61K39/39

CPC分类号： A61K39/145 ,  A61K39/12 ,  A61K39/39 ,  A61K2039/5252 ,  A61K2039/543 ,  A61K2039/55511 ,  A61K2039/55588 ,  A61K2039/58 ,  C12N7/00 ,  C12N2760/16134 ,  Y02A50/388 ,  Y02A50/466

摘要： The invention relates to a composition for use as an intranasally administered vaccine comprising one or more non-live influenza virus antigens, and
an adjuvant comprising:
one or more carboxylic acids,
an aqueous medium, and
optionally one or more mono-glycerides.

摘要翻译： 本发明涉及用作鼻内施用疫苗的组合物，其包含一种或多种非活流感病毒抗原和佐剂，所述佐剂包含：一种或多种羧酸，水性介质和任选的一种或多种单甘油酯。