专利检索 ap:("Eurona Medical AB") AND inv:"JONSSON, Lena" 第 1 页

1.

发明公开
GENES FOR ASSESSING CARDIOVASCULAR STATUS AND COMPOSITIONS FOR USE THEREOF 审中-公开
标题翻译：基因领养心血管疾病和使用的化合物FOR THE作者：

公开(公告)号：EP1121462A2

公开(公告)日：2001-08-08

申请号：EP99947799.5

申请日：1999-10-13

申请人： Eurona Medical AB

发明人： NORBERG, Leif, Torbjorn , ANDERSSON, Maria, Kristina , LINDSTROM, Per, Harry, Rutger , JONSSON, Lena

IPC分类号： C12Q1/68 , C07K14/705 , C12N9/64 , C07K14/72 , C12N9/02

CPC分类号： C12N9/0079 , C07K14/70571 , C07K14/72 , C12N9/6486 , C12Q1/6883 , C12Q2600/106 , C12Q2600/156 , C12Y304/23015

摘要： The present invention provides methods for assessing cardiovascular status in an individual, which comprise determining the sequence at one or more polymorphic positions within the human genes encoding ACE, AT1, AGT, renin, aldosterone synthase, type-2 angiotensin II receptor, endothelin receptor, and β-adrenoceptor. The invention also provides isolated nucleic acids encoding polymorphisms in genes encoding ACE, AT1, AGT, renin, aldosterone synthase, type-2 angiotensin II receptor, endothelin receptor and β-adrenoceptor, nucleic acid probes that hybridized to polymorphic positions, kits for the prediction of cardiovascular status, and nucleic acid and peptide targets for use in identifying candidate cardiovascular drugs.