公开(公告)号：EP2066622A1

公开(公告)日：2009-06-10

申请号：EP06793479.4

申请日：2006-09-13

申请人： Evonik Degussa GmbH

发明人： WERLE, Peter ,  MERZ, Friedhelm ,  TRAGESER, Martin

IPC分类号： C07C277/02 ,  C07C279/28

CPC分类号： C07C277/08 ,  C07C279/26 ,  C07C279/28

摘要： The present invention is directed to a process for preparing hexamethylenebiscyanoguanidine. This compound is used as an intermediate to prepare chlorhexidine. The formation of the hexamethylenebiscyanoguanidine proceeds under base catalysis in an organic solvent. The base used in accordance with the invention is chlorhexidine itself. In addition, this invention enables the preparation of chlorhexidine base in a so-called one-pot process without intermediate isolation of the HMBCG.

公开(公告)号：EP2066622B1

公开(公告)日：2013-11-06

申请号：EP06793479.4

申请日：2006-09-13

申请人： Evonik Degussa GmbH

发明人： WERLE, Peter ,  MERZ, Friedhelm ,  TRAGESER, Martin

IPC分类号： C07C277/08 ,  C07C279/28

CPC分类号： C07C277/08 ,  C07C279/26 ,  C07C279/28