VERFAHREN ZUR HERSTELLUNG VON PHENYLENBISOXAZOLINEN

    公开(公告)号:EP2326630A1

    公开(公告)日:2011-06-01

    申请号:EP09815657.3

    申请日:2009-08-07

    IPC分类号: C07D263/10

    CPC分类号: C07D263/10 Y02P20/582

    摘要: The invention relates to a method for producing heterocylces of the formula (I) by the catalytic reaction of an aromatic dinitrile of the formula using an amino alcohol, characterized in that the amino alcohol and the catalyst are provided and the aromatic dinitrile is added at a reaction temperature, wherein any further solvent is dispensed with during the reaction, and subsequently the excess of amino alcohol is completely removed by distillation after completion of the reaction, wherein the reaction mixture is continuously moved and subsequently the catalyst is removed by means of washing utilizing alcohol.

    摘要翻译: 本发明涉及一种通过使用氨基醇通过下式的芳族二腈的催化反应制备式(I)的杂环的方法,其特征在于提供氨基醇和催化剂,并且芳族二腈在 反应温度,其中在反应过程中分配任何其他溶剂,随后在反应完成后通过蒸馏完全除去过量的氨基醇,其中反应混合物连续移动,随后通过利用洗涤除去催化剂 醇。