PROCESS FOR PREPARING N-SUBSTITUTED CYCLIC IMIDES
    7.
    发明公开
    PROCESS FOR PREPARING N-SUBSTITUTED CYCLIC IMIDES 有权
    用于制备N-取代的环状酰亚胺

    公开(公告)号:EP2414329A2

    公开(公告)日:2012-02-08

    申请号:EP10764788.5

    申请日:2010-02-01

    发明人: JAENSCH, Helge

    IPC分类号: C07D209/48 C07D209/44

    CPC分类号: C07D209/48

    摘要: In a process for making an N-substituted phthalimide compound, an amine is contacted with a carboxylic acid anhydride and allowed to react in an aqueous solution at a pH of about 2 to about 6. Optionally, the reactants are combined with an acid to lower the pH of the reaction solution wherein the lowering of the pH optimizes the yield of the desired N-substituted phthalimide product. The N-substituted phthalimide may be, for example, N-hydroxyphthalimide, and the reactants may be phthalic anhydride and hydroxylamine or a salt thereof. The N-substituted phthalimide compound is useful for, among other things, the oxidation of various hydrocarbons.