COMBINATION THERAPY OF BISPECIFIC ANTIBODIES SPECIFIC FOR FAP AND DR5 AND CHEMOTHERAPEUTIC AGENTS
    3.
    发明公开
    COMBINATION THERAPY OF BISPECIFIC ANTIBODIES SPECIFIC FOR FAP AND DR5 AND CHEMOTHERAPEUTIC AGENTS 审中-公开
    FAP和DR5与化疗药物特异性双特异性抗体的联合治疗

    公开(公告)号:EP3204412A2

    公开(公告)日:2017-08-16

    申请号:EP15774630.6

    申请日:2015-10-06

    IPC分类号: C07K16/22 C07K16/28 C07K16/40

    摘要: The present invention relates to bispecific antibodies comprising at least one antigen binding site specific for DR5 and at least one antigen binding site specific for FAP, antibodies specific for DR5, and in particular to combination therapies employing such bispecific antibodies and a chemotherapeutic agent, and their use of these combination therapies for the treatment of cancer.

    摘要翻译: 本发明涉及双特异性抗体,其包含对DR5具有特异性的至少一个抗原结合位点和对FAP特异性的至少一个抗原结合位点,对DR5具有特异性的抗体,并且具体地涉及使用此类双特异性抗体和化学治疗剂的组合疗法及其它 使用这些联合疗法治疗癌症。