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公开(公告)号：EP4294566A1
公开(公告)日：2023-12-27
申请号：EP22708855.6
申请日：2022-02-15
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2.发明公开
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3.发明公开
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公开(公告)号：EP4352675A1
公开(公告)日：2024-04-17
申请号：EP22731709.6
申请日：2022-06-08
发明人： HEINEMEYER, Thomas , KEMPKEN, Dieter , ROETZER, Marian , SCHEINPFLUG, Lorenz , SCHWEINBERGER, Florian
CPC分类号： G16H40/63 , G06Q10/0637 , G04F1/005
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公开(公告)号：EP4006953A1
公开(公告)日：2022-06-01
申请号：EP20210212.5
申请日：2020-11-27
摘要： In one general aspect, the present disclosure relates to a packaging for a needle-like component of a mass spectrometry (MS) system. The packaging includes a receptacle configured for storing the needle-like component in a secured position inside the receptacle.
The packaging further comprises an actuator configured to move the needle-like component from the secured position inside the receptacle to a mounting position in which the needle-like component projects out of the receptacle for mounting the needle-like component to the MS system.-
公开(公告)号：EP3992627A1
公开(公告)日：2022-05-04
申请号：EP20204420.2
申请日：2020-10-28
IPC分类号： G01N30/72
摘要： The LC-MS apparatus includes an ionization source 51 coupled to a mass spectrometer 50 and a liquid chromatographic (LC) system 10 coupled to the ionization source. The LC system 10 comprises multiple fluidic streams 11,12,13 alternately connectable to the ionization source 51, thereby assigning a detection time window to each fluidic stream from the multiple fluidic streams when connected to the ionization source. The LC-MS apparatus further comprises a controller 60 that is configured to carry out steps of monitoring an ionization current of the ionization source 51 for the multiple fluidic streams and identifying differences in flow conditions between the multiple fluidic streams based on the monitored ionization current. The controller is further configured to carry out adjusting detection conditions of one or more of the multiple fluidic streams responsive to the identified differences.
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公开(公告)号：EP3840014A1
公开(公告)日：2021-06-23
申请号：EP19217080.1
申请日：2019-12-17
发明人： QUINT, Stefan , ROETZER, Marian , SCHWEINBERGER, Florian , TIEMANN, Benjamin , WAGNER, Marius , ZIMMERMAN, Ralf
摘要： An analytical system (100) comprising a mass spectrometer (MS) (40) coupled to liquid chromatography (LC) (20) via an ionization source (IS) (30) and an automated method of maintaining the analytical system (100) in a QC-compliant status are described. The method comprises determining a deviation of the analytical system (100) from a QC-compliant status by determining a deviation of one or more predetermined parameters (1, 2) in an m/z spectrum (11) above one or more predetermined thresholds, triggering an IS and/or MS maintenance procedure (12) upon determining a deviation from the QC-compliant status, determining (13) a return or a failed return to the QC-compliant status during and/or after the IS and/or MS maintenance procedure (12) by determining a return or a failed return respectively of the one or more predetermined parameters (1, 2) in an m/z spectrum (14, 16) below the one or more predetermined thresholds, triggering another IS and/or MS maintenance procedure (15) upon determining a failed return to the QC-compliant status.
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公开(公告)号：EP3761038A1
公开(公告)日：2021-01-06
申请号：EP19184462.0
申请日：2019-07-04
摘要： In one general aspect, the present invention relates to an automated method for identifying a clot or a leak in an analyzer including multiple liquid chromatography (LC) streams, the method includes obtaining an indication of a trigger event for a clot or leak detection routine and starting a clot or leak detecting routine in response to the trigger event. The clot or leak detecting routine is designed to identify a location of the clot or leak out multiple possible positions by using one or more sensors of the analyzer. The method further includes providing information regarding the identified location of the clot or leak for further processing.
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