专利检索 ap:("F.HOFFMANN-LA ROCHE AG") AND inv:"GOBBI, Luca, Claudio" 第 1 页

1.

发明公开
N-(4-CARBAMIMIDOYL-BENZYL)-2-ALKOXY-2-HETEROCYCLYL ACETAMIDES AS INHIBITORS OF THE FORMATION OF COAGULATION FACTORS XA, IXA AND THROMBIN INDUCED BY FACTOR VIIA 审中-公开
标题翻译： N-（4-脒基苄基）凝结的形成-2 - 烷氧基-2- HETEROCYCLYLACETAMIDE ALS抑制剂因子XA，IXA和凝血酶通过因子VIIA诱导

公开(公告)号：EP1706396A1

公开(公告)日：2006-10-04

申请号：EP04803815.2

申请日：2004-12-13

申请人： F.HOFFMANN-LA ROCHE AG

发明人： GOBBI, Luca, Claudio , GROEBKE ZBINDEN, Katrin , MOHR, Peter , OBST, Ulrike

IPC分类号： C07D401/04 , C07D249/08 , C07D231/12 , C07D209/48 , C07D263/32 , C07D235/16 , C07D213/76 , C07D213/74 , C07D413/12 , C07D401/12 , A61P7/02

CPC分类号： C07D401/04 , C07D209/46 , C07D209/48 , C07D213/64 , C07D213/74 , C07D213/76 , C07D231/12 , C07D235/16 , C07D249/08 , C07D263/32 , C07D271/06 , C07D401/12 , C07D413/12

摘要： The invention is concerned with novel heterocyclyl substituted mandelic acid derivatives of formula (I) wherein R1 to R6 and A are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the formation of coagulation factors Xa, IXa and thrombin induced by factor VIIa and tissue factor and can be used as medicaments.