公开(公告)号：EP1756054B1

公开(公告)日：2010-03-31

申请号：EP05747507.1

申请日：2005-05-27

申请人： F.HOFFMANN-LA ROCHE AG

发明人： GREENHOUSE, Robert ,  JAIME-FIGUEROA, Saul ,  RAPTOVA, Lubica ,  REUTER, Deborah, Carol ,  STEIN, Karin, Ann ,  WEIKERT, Robert, James

IPC分类号： C07D209/04 ,  A61K31/4045

CPC分类号： C07D401/06 ,  C07D209/08 ,  C07D209/14 ,  C07D231/56 ,  C07D307/14

摘要： Compounds of formula I: or pharmaceutically acceptable salts thereof, wherein p, Ar, R1, R2, R3, Ra, Rb, Rc, Rd and Re are defined herein, pharmaceutical compositions containing them and methods of using them for the preparation of medicaments for treating depression or anxiety.

公开(公告)号：EP1756054A1

公开(公告)日：2007-02-28

申请号：EP05747507.1

申请日：2005-05-27

申请人： F.HOFFMANN-LA ROCHE AG

发明人： GREENHOUSE, Robert ,  JAIME-FIGUEROA, Saul ,  RAPTOVA, Lubica ,  REUTER, Deborah, Carol ,  STEIN, Karin, Ann ,  WEIKERT, Robert, James

IPC分类号： C07D209/04 ,  A61K31/4045

CPC分类号： C07D401/06 ,  C07D209/08 ,  C07D209/14 ,  C07D231/56 ,  C07D307/14

摘要： Compounds of formula I: or pharmaceutically acceptable salts thereof, wherein p, Ar, R1, R2, R3, Ra, Rb, Rc, Rd and Re are defined herein, pharmaceutical compositions containing them and methods of using them for the preparation of medicaments for treating depression or anxiety.