专利检索 ap:("F.HOFFMANN-LA ROCHE AG") AND inv:"WESSEL, Hans, Peter" 第 1 页

1.

发明授权
HEXAHYDROPYRIDOISOQINOLINES AS DPP-IV INHIBITORS 有权
标题翻译： HEXAHYDROPYRIDOISOCHINOLINE AS DPP-IV抑制剂

公开(公告)号：EP1638968B1

公开(公告)日：2009-07-29

申请号：EP04739825.0

申请日：2004-06-11

申请人： F.HOFFMANN-LA ROCHE AG

发明人： BOEHRINGER, Markus , KUHN, Bernd , LUEBBERS, Thomas , MATTEI, Patrizio , NARQUIZIAN, Robert , WESSEL, Hans, Peter

IPC分类号： C07D471/04 , A61K31/4745 , A61P5/50

CPC分类号： C07D471/04 , A61K31/4745

摘要： The present invention relates to compounds of formula (I) wherein R1 is as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP-IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.

2.

发明公开
SUBSTITUTED BENZOQUINOLIZINES AS DPP-IV INHIBITORS FOR THE TREATMENT OF DIABETES 审中-公开
标题翻译：取代benzoquinolizines AS DPP-IV抑制剂用于糖尿病的治疗

公开(公告)号：EP1851216A2

公开(公告)日：2007-11-07

申请号：EP05807340.4

申请日：2005-11-21

申请人： F.HOFFMANN-LA ROCHE AG

发明人： BOEHRINGER, Markus , HUNZIKER, Daniel , KUHN, Bernd , LOEFFLER, Bernd, Michael , RICKLIN, Fabienne , WESSEL, Hans, Peter

IPC分类号： C07D471/04 , A61K31/4745 , A61P3/10

CPC分类号： C07D455/06

摘要： The present invention relates to compounds of formula (I); wherein R1 to R4 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP-IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.

3.

发明公开
HEXAHYDROPYRIDOISOQINOLINES AS DPP-IV INHIBITORS 有权
标题翻译：作为DPP-IV抑制剂的六氢吡啶并异喹啉

公开(公告)号：EP1638968A1

公开(公告)日：2006-03-29

申请号：EP04739825.0

申请日：2004-06-11

申请人： F.HOFFMANN-LA ROCHE AG

发明人： BOEHRINGER, Markus , KUHN, Bernd , LUEBBERS, Thomas , MATTEI, Patrizio , NARQUIZIAN, Robert , WESSEL, Hans, Peter

IPC分类号： C07D471/04 , A61K31/4745 , A61P5/50

CPC分类号： C07D471/04 , A61K31/4745

摘要： The present invention relates to compounds of formula (I) wherein R1 is as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP-IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.

摘要翻译： 本发明涉及其中R 1如说明书和权利要求书中所定义的式（I）化合物及其药学上可接受的盐。该化合物可用于治疗和/或预防与DPP-IV相关的疾病，例如糖尿病，特别是非胰岛素依赖性糖尿病和葡萄糖耐量降低。