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公开(公告)号:EP2550295A1
公开(公告)日:2013-01-30
申请号:EP11711425.6
申请日:2011-03-23
发明人: BOURHIS, Eric , CARANO, Rick , COCHRAN, Andrea , COSTA, Mike , DE ALMEIDA, Venita , ERNST, James , GONG, Yan , HANNOUSH, Rami , POLAKIS, Paul , RUBINFELD, Bonnee , SOLLOWAY, Mark , WU, Yan , CAO, Tim Christopher
IPC分类号: C07K16/28 , A61K39/395 , A61P35/00
CPC分类号: C07K16/28 , A61K39/3955 , A61K2039/505 , A61K2039/507 , C07K16/2863 , C07K2317/21 , C07K2317/31 , C07K2317/34 , C07K2317/526 , C07K2317/55 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2319/00
摘要: The invention provides anti-LRP6 antibodies and methods of using the same. A particular aspect of the invention provides for bispecific anti-LRP6 antibodies that inhibit signaling by multiple Wnt isoforms.