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    HSL INHIBITORS USEFUL IN THE TREATMENT OF DIABETES
    4.
    发明公开
    HSL INHIBITORS USEFUL IN THE TREATMENT OF DIABETES 有权
    HSL抑制剂治疗糖尿病

    公开(公告)号：EP2475644A1

    公开(公告)日：2012-07-18

    申请号：EP10751931.6

    申请日：2010-09-07

    申请人： F.Hoffmann-La Roche AG

    发明人： ACKERMANN, Jean ,  CONTE, Aurelia ,  NEIDHART, Werner ,  NETTEKOVEN, Matthias ,  WERTHEIMER, Stanley

    IPC分类号： C07D211/62 ,  C07D211/96 ,  C07D401/12 ,  C07D405/12 ,  A61K31/445 ,  A61P3/00 ,  A61P9/10

    CPC分类号： C07D211/96 ,  C07D211/62 ,  C07D401/12 ,  C07D405/12

    摘要： Compounds of formula (I), as well as pharmaceutically acceptable salts thereof can be used in the form of pharmaceutical compositions, wherein A
    1 , A
    2 , R
    1 ,R
    2 R
    3 ,R
    4 R
    5 and R
    6 have the significance given in claim 1. Objects of the present invention are the compounds of formula (I) and their aforementioned salts and esters and their use as therapeutically active substances, a process for the manufacture of the said compounds, intermediates, pharmaceutical compositions, medicaments containing the said compounds, their pharmaceutically acceptable salts or esters, the use of the said compounds, salts or esters for the treatment or prophylaxis of illnesses, especially in the treatment or prophylaxis of diabetes, metabolic syndrome, dyslipidemia, atherosclerosis or obesity and the use of the said compounds, salts or esters for the production of medicaments for the treatment or prophylaxis of diabetes, metabolic syndrome, dyslipidemia, atherosclerosis or obesity.