公开(公告)号：EP1272610A1

公开(公告)日：2003-01-08

申请号：EP01921556.5

申请日：2001-04-11

申请人： F2G Limited

发明人： DENNING, David Wemys ,  BROOKMAN, Jayne Louise ,  RICKERS, Andre ,  BIRCH, Mike

IPC分类号： C12N1/16 ,  C12N15/80 ,  A61K48/00

CPC分类号： C12N15/1082 ,  A61K48/00 ,  C07K14/38 ,  C12N15/80 ,  C12N15/815

摘要： The invention relates to a mutant bank of diploid micro-organisms which consists of a population of mutant cells in which at least one cell has a random mutation which disrupts the activity of at least one gene, wherein the micro-organism is inducible into haploid form. The invention further relates to a method of using the mutant bank to identify the genes which contribute to a chosen phenotype.

公开(公告)号：EP2283006B1

公开(公告)日：2015-02-25

申请号：EP09734928.6

申请日：2009-04-23

申请人： F2G Limited

发明人： SIBLEY, Graham, Edward, Morris ,  DOWNHAM, Robert ,  PAYNE, Lloyd, James ,  LAW, Derek ,  OLIVER, Jason, David ,  BIRCH, Mike ,  DAVIES, Gareth, Morse

IPC分类号： C07D401/12 ,  A01N43/40 ,  A01N43/42 ,  A61P31/10

CPC分类号： A61K31/5377 ,  A01N43/36 ,  A01N43/40 ,  A01N43/42 ,  A01N43/60 ,  A01N43/76 ,  A01N43/84 ,  A01N43/90 ,  A61K31/4025 ,  A61K31/4439 ,  A61K31/4709 ,  A61K31/4725 ,  A61K31/496 ,  A61K31/4985 ,  A61K45/06 ,  C07D487/04 ,  C07D498/04

公开(公告)号：EP2283006A1

公开(公告)日：2011-02-16

申请号：EP09734928.6

申请日：2009-04-23

申请人： F2G Limited

发明人： SIBLEY, Graham, Edward, Morris ,  DOWNHAM, Robert ,  PAYNE, Lloyd, James ,  LAW, Derek ,  OLIVER, Jason, David ,  BIRCH, Mike ,  DAVIES, Gareth, Morse

IPC分类号： C07D401/12 ,  A01N43/40 ,  A01N43/42 ,  A61P31/10

CPC分类号： A61K31/5377 ,  A01N43/36 ,  A01N43/40 ,  A01N43/42 ,  A01N43/60 ,  A01N43/76 ,  A01N43/84 ,  A01N43/90 ,  A61K31/4025 ,  A61K31/4439 ,  A61K31/4709 ,  A61K31/4725 ,  A61K31/496 ,  A61K31/4985 ,  A61K45/06 ,  C07D487/04 ,  C07D498/04

摘要： The invention provides compounds of formula (I), and pharmaceutically and agriculturally acceptable salts thereof; wherein: R1, R2, R3, R4, R5, R6, A1, L1 and n are as defined herein. These compounds and their pharmaceutically acceptable salts are useful in prevention or treatment of a fungal disease. Compounds of formula (I), and agriculturally acceptable salts thereof, may also be used as agricultural fungicides.