公开(公告)号：EP1697519B1

公开(公告)日：2009-03-04

申请号：EP04798949.6

申请日：2004-11-19

申请人： FIRMENICH SA

发明人： SCHALK, Michel ,  DEGUERRY Fabienne c/o FIRMENICH SA

IPC分类号： C12N15/60 ,  C12N9/88 ,  C12N5/10 ,  C12N1/21

CPC分类号： C12P7/22 ,  C12N9/88 ,  C12P5/007 ,  C12P15/00

摘要： The invention relates to sesquiterpene synthases from Patchouli plants (Pogostemon cablin), and methods of their production and use. In one embodiment, the invention provides nucleic acids comprising a nucleotide sequence as described herein that encodes for at least one sesquiterpene synthase. In a further embodiment, the invention also provides for sesquiterpene synthases and methods of making and using these enzymes. For example, sesquiterpene synthases of the invention may be used to convert farnesyl-pyrophosphate to various sesquiterpenes including patchoulol, Ϝ-curcumene and other germacrane-type sesquiterpenes.