公开(公告)号：EP0031645A3

公开(公告)日：1981-07-15

申请号：EP80304149

申请日：1980-11-20

申请人： FISONS plc

发明人： Whitmore, Martyn William ,  Pollard, Michael David ,  Smythe, Stephen Richard

IPC分类号： C07C107/02 ,  C08F04/04 ,  C07D231/18

CPC分类号： C07C255/65 ,  C08F4/04

摘要： There is described a process for the production of a compound of formula I,
in which at least one each of Ri, R 2 and R 3 , and of R 4 , R 5 and R 6 , represents an electron withdrawing group, or one of R 1 , R 2 and R 3 together with one of R 4 , R 5 and R 6 form a -CO- group, and the remainder of Ri, R 2 , R 3 , R 4 , R 5 and R 6 , which may be the same or different, each represent an electron withdrawing group, alkyl, cycloalkyl, phenyl or phenylalkyl,
or R 1 and R 2 , or R 4 and R 5 , and R 1 and R 4 , may together form a -(CH 2 )n- chain, in which n is a whole number up to 5, the alkyl, cycloalkyl, phenyl or phenylalkyl group or the -(CH 2 ) n ,- chain optionally being substituted, which comprises reacting a compound of formula II,
in which Ria, R 2 a and R 3 a have the same significances as Ri, R 2 , and R 3 above, and some additional significances, with a compound of formula III,
in which R 4 a, R 5 a and R 6 a have the same significances as R 4 , R 5 and R 6 above, and some additional significances, the reaction being carried out in an aqueous medium in the presence of a base and a surfactant.