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公开(公告)号：EP3849777A1
公开(公告)日：2021-07-21
申请号：EP19758985.6
申请日：2019-08-28
IPC分类号： B29C64/106 , B29C64/364 , B33Y10/00 , B33Y30/00 , A61L27/52 , C12N5/00
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公开(公告)号：EP4333914A1
公开(公告)日：2024-03-13
申请号：EP22726066.8
申请日：2022-04-27
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公开(公告)号：EP3623136A1
公开(公告)日：2020-03-18
申请号：EP18194428.1
申请日：2018-09-14
IPC分类号： B29C64/106 , B29C64/364 , B33Y10/00 , B33Y30/00 , A61L27/52 , C12N5/00
摘要： The invention relates to a method for producing three-dimensional, preferably porous, hydrogel structures (1) by means of layer build-up technique, wherein the method comprises the following steps. Providing (S1) of a liquid hydrogel solution, preferably a liquid alginate solution, and a, preferably transportable, sample carrier. Layerwise applying (S2) the liquid hydrogel solution onto the sample carrier (4) in a temperature environment, the temperature of which is below the freezing point of the hydrogel solution, to produce a frozen 3D layered hydrogel structure (1a). In order to increase advantageously the porosity of the 3D layered hydrogel structure (1a), i.e. the proportion of small voids, cavities and/or depressions in the 3D layered hydrogel structure, the method according to the invention further comprises the step of drying (S3) of the frozen 3D layered hydrogel structure (1a), e.g. by means of freeze-drying, to produce a porous 3D hydrogel structure (1). The invention relates further also to a device (10) for the layerwise building-up of three-dimensional hydrogel structures.
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5.发明公开
公开(公告)号：EP3576723A1
公开(公告)日：2019-12-11
申请号：EP18701427.9
申请日：2018-01-18
申请人： Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. , Universität des Saarlandes
发明人： ZIMMERMANN, Heiko , VON BRIESEN, Hagen , SCHULZ, Andre , ELBERSKIRCH, Linda , WAGNER, Sylvia , FISCHER, Benjamin
IPC分类号： A61K9/48 , C12Q1/26 , G01N33/574 , A61P35/00
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