公开(公告)号：EP0407701A3

公开(公告)日：1992-04-22

申请号：EP90108717.1

申请日：1990-05-09

申请人： FUJISAWA PHARMACEUTICAL CO., LTD.

发明人： Takatsuki, Kiyoshi ,  Maeda, Yohsuke ,  Hattori, Toshio ,  Kaizu, Tsutomu ,  Okamoto, Masanori ,  Yokota, Yoshiko ,  Nakamura, Katsuya ,  Kayakiri, Hiroshi

IPC分类号： A61K31/40 ,  C07D207/12 ,  C07H5/10

CPC分类号： C07H5/06 ,  A61K31/40 ,  A61K31/70 ,  C07D207/12 ,  C07D207/24 ,  C07H5/10

摘要： A use of a pyrroline compound of the formula:

or its sulfurous acid adduct, or a pharmaceutically acceptable salt thereof for manufacturing a medicament for treating infectious diseases cause by retrovirus, and a process for preparing a medicament containing such compound. The invention also relates to a pyrroline-sulfurous acid adduct of the formula:

and a pharmaceutically acceptable salt thereof, a process for preparing it and a pharmaceutical composition comprising it.

公开(公告)号：EP0407701A2

公开(公告)日：1991-01-16

申请号：EP90108717.1

申请日：1990-05-09

申请人： FUJISAWA PHARMACEUTICAL CO., LTD.

发明人： Takatsuki, Kiyoshi ,  Maeda, Yohsuke ,  Hattori, Toshio ,  Kaizu, Tsutomu ,  Okamoto, Masanori ,  Yokota, Yoshiko ,  Nakamura, Katsuya ,  Kayakiri, Hiroshi

IPC分类号： A61K31/40 ,  C07D207/12 ,  C07H5/10

CPC分类号： C07H5/06 ,  A61K31/40 ,  A61K31/70 ,  C07D207/12 ,  C07D207/24 ,  C07H5/10

摘要： A use of a pyrroline compound of the formula:

or its sulfurous acid adduct, or a pharmaceutically acceptable salt thereof for manufacturing a medicament for treating infectious diseases cause by retrovirus, and a process for preparing a medicament containing such compound. The invention also relates to a pyrroline-sulfurous acid adduct of the formula:

and a pharmaceutically acceptable salt thereof, a process for preparing it and a pharmaceutical composition comprising it.

摘要翻译： 下式的吡咯啉化合物或其亚硫酸加成物或其药学上可接受的盐在制备用于治疗由逆转录病毒引起的感染性疾病的药物中的用途，以及制备含有该化合物的药物的方法。 本发明还涉及下式的吡咯啉 - 亚硫酸加合物及其药学上可接受的盐，其制备方法和包含它的药物组合物。