公开(公告)号：EP2785350A2

公开(公告)日：2014-10-08

申请号：EP12852924.5

申请日：2012-11-29

申请人： Fate Therapeutics, Inc.

发明人： SHOEMAKER, Dan ,  MULTANI, Pratik, S. ,  MENDLEIN, John, D. ,  ROBBINS, David

IPC分类号： A61K31/5575 ,  A61K31/573 ,  A61P9/10 ,  A61P9/00

CPC分类号： A61K35/28 ,  A61K31/5575 ,  A61K31/573 ,  A61K2035/124 ,  C12N5/0647 ,  C12N2501/02 ,  C12N2501/39 ,  A61K2300/00

公开(公告)号：EP2785350B1

公开(公告)日：2018-05-02

申请号：EP12852924.5

申请日：2012-11-29

申请人： Fate Therapeutics, Inc.

发明人： SHOEMAKER, Dan ,  MULTANI, Pratik, S. ,  MENDLEIN, John, D. ,  ROBBINS, David

IPC分类号： A61K31/5575 ,  A61K31/573 ,  A61P9/10 ,  A61P9/00 ,  A61K35/28 ,  C12N5/0789 ,  A61K35/12

CPC分类号： A61K35/28 ,  A61K31/5575 ,  A61K31/573 ,  A61K2035/124 ,  C12N5/0647 ,  C12N2501/02 ,  C12N2501/39 ,  A61K2300/00

摘要： The invention provides compositions comprising stem and/or progenitor cells that have been treated to enhance the therapeutic properties of the cells for treating ischemia. In particular, the present invention relates to the use of stem and/or progenitor cells having enhanced therapeutic properties to treat an ischemic tissue, a tissue damaged by ischemia, or at least one symptom associated with an ischemic tissue or a tissue damaged by ischemia.