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公开(公告)号：EP3762482A1
公开(公告)日：2021-01-13
申请号：EP19764743.1
申请日：2019-03-08
发明人： LIPKENS, Bart , TOSTOES, Rui , DUTRA, Brian , GILMANSHIN, Rudolf , DIONNE, Jason , PRESZ, Walter, M., Jr. , ROSS-JOHNSRUD, Benjamin , GHOSHAL, Goutam , CHITALE, Kedar
IPC分类号： C12N5/0783 , C12N5/00 , C12N13/00 , C12M1/00
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2.发明公开ACOUSTOPHORETIC SEPARATION OF LIPID PARTICLES FROM RED BLOOD CELLS 有权AKUSTOPHORETISCHE TRENNUNG VON LIPIDPARTIKELN AUS ROTENBLUTKÖRPERCHEN
公开(公告)号：EP2838582A1
公开(公告)日：2015-02-25
申请号：EP13721179.3
申请日：2013-04-19
发明人： DUTRA, Brian , LIPKENS, Bart
IPC分类号： A61M1/38
CPC分类号： A61M1/3681 , A61M1/363 , A61M1/3678 , A61M2202/08 , B01D21/283
摘要： A system for removing lipids from blood during cardiopulmonary bypass surgery is disclosed. The system uses an acoustophoretic separator having improved trapping force. The transducer of the acoustophoretic seperator includes a ceramic crystal. Blood flows through the separator, and lipids are trapped and removed.
摘要翻译： 公开了一种在体外循环手术期间从血液中除去脂质的系统。 该系统使用具有改进的捕获力的声学分离器。 声波分离器的换能器包括陶瓷晶体。 血液流过分离器，脂质被捕获并除去。
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公开(公告)号：EP3481361A1
公开(公告)日：2019-05-15
申请号：EP17723852.4
申请日：2017-05-03
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公开(公告)号：EP3737738A1
公开(公告)日：2020-11-18
申请号：EP19738317.7
申请日：2019-01-09
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公开(公告)号：EP3500659A1
公开(公告)日：2019-06-26
申请号：EP16754152.3
申请日：2016-08-16
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公开(公告)号：EP3319739A1
公开(公告)日：2018-05-16
申请号：EP16753490.8
申请日：2016-07-09
发明人： LIPKENS, Bart , PRESZ, Walter, M., Jr. , CHITALE, Kedar , KENNEDY, Thomas, J., III , GILMANSHIN, Rudolf , MEALEY, Dane , DUTRA, Brian , SOKOLOWSKI, David
CPC分类号： B06B1/0238 , B01D21/0009 , B01D21/283 , B06B1/0644 , B06B3/04 , C12M47/02 , H03H9/17
摘要： An acoustophoretic device is disclosed. The acoustophoretic device includes an acoustic chamber, an ultrasonic transducer, and a reflector. The ultrasonic transducer includes a piezoelectric material driven by a voltage signal to create a multi-dimensional acoustic standing wave in the acoustic chamber emanating from a non-planar face of the piezoelectric material. A method for separating a second fluid or a particulate from a host fluid is also disclosed. The method includes flowing the mixture through an acoustophoretic device. A voltage signal is sent to drive the ultrasonic transducer to create the multi-dimensional acoustic standing wave in the acoustic chamber such that the second fluid or particulate is continuously trapped in the standing wave, and then agglomerates, aggregates, clumps, or coalesces together, and subsequently rises or settles out of the host fluid due to buoyancy or gravity forces, and exits the acoustic chamber.
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公开(公告)号：EP2838582B1
公开(公告)日：2018-01-10
申请号：EP13721179.3
申请日：2013-04-19
发明人： DUTRA, Brian , LIPKENS, Bart
IPC分类号： A61M1/38
CPC分类号： A61M1/3681 , A61M1/363 , A61M1/3678 , A61M2202/08 , B01D21/283
摘要： A system for removing lipids from blood during cardiopulmonary bypass surgery is disclosed. The system uses an acoustophoretic separator having improved trapping force. The transducer of the acoustophoretic seperator includes a ceramic crystal. Blood flows through the separator, and lipids are trapped and removed.
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公开(公告)号：EP2953700A1
公开(公告)日：2015-12-16
申请号：EP14749278.9
申请日：2014-02-07
发明人： LIPKENS, Bart , MASI, Louis , KOWALSKI III, Stanley , PRESZ, Walter M. jr. , DIONNE, Jason , DUTRA, Brian , MERCADO, Ari , KENNEDY III, Thomas , MARTIN, Arthur
IPC分类号： B01D21/28
CPC分类号： C12M47/06 , B01D21/283 , C12M29/10 , C12M33/08 , C12M47/02
摘要： A perfusion bioreactor includes at least one ultrasonic transducer that can acoustically generate a multi-dimensional standing wave. The standing wave can be used to retain cells in the bioreactor, and can also be utilized to dewater or further harvest product from the waste materials produced in a bioreactor. The bioreactor includes a reaction vessel, an agitator, a feed inlet, and an outlet. A filtering device is included that has an inlet, a flow chamber and a sleeve surrounding the flow chamber, where the sleeve includes the ultrasonic transducer.
摘要翻译： 灌注生物反应器包括至少一个可声学地产生多维驻波的超声换能器。 驻波可用于将细胞保留在生物反应器中，并且还可用于从生物反应器中生产的废物中脱水或进一步收获产品。 生物反应器包括反应容器，搅拌器，进料口和出口。 包括过滤装置，其具有入口，流动室和围绕流动室的套筒，其中套筒包括超声换能器。
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9.发明公开IMPROVED SEPARATION OF MULTI-COMPONENT FLUID THROUGH ULTRASONIC ACOUSTOPHORESIS 审中-公开BY超声acoustophoresis多份流体改善分离
公开(公告)号：EP2872234A1
公开(公告)日：2015-05-20
申请号：EP13742354.7
申请日：2013-07-16
发明人： LIPKENS, Bart , DIONNE, Jason , MERCADO, Ari , DUTRA, Brian , PRESZ, Walter, Jr. , MASI, Louis , KENNEDY, Thomas J., III
CPC分类号： B01D17/045 , B06B1/0644 , C02F1/36 , C02F1/40 , C12M47/02
摘要： An acoustic standing wave is utilized to separate components from a multi- component fluid, such as oil from an oil-water mixture, in a fluid flow scheme with an acoustophoresis device. For example, the flow scheme and device allows for trapping of the oil as the oil coalesces, agglomerates, and becomes more buoyant than the water.
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