公开(公告)号：EP2988842A1

公开(公告)日：2016-03-02

申请号：EP14787587.6

申请日：2014-04-25

申请人： Flodesign Sonics Inc.

发明人： LIPKENS, Bart ,  MERCADO, Ari ,  MARTIN, Arthur ,  MASI, Louis ,  DIONNE, Jason

IPC分类号： B01D11/00

CPC分类号： B01D21/00 ,  B01D11/0223 ,  B01D11/0265 ,  B01D21/283 ,  B01D2221/10 ,  G01N33/15

摘要： Active pharmaceutical ingredients can be separated from their excipients by dissolving a pharmaceutical product (e.g. tablet, pill) into a solvent, then running the solution through an acoustophoretic device. Standing waves are used to separate the excipient from the active ingredient dissolved in the solvent.

公开(公告)号：EP3500659A1

公开(公告)日：2019-06-26

申请号：EP16754152.3

申请日：2016-08-16

申请人： Flodesign Sonics, Inc.

发明人： LIPKENS, Bart ,  MASI, Louis ,  KOWALSKI, III, Stanley ,  PRESZ, JR., Walter M. ,  DIONNE, Jason ,  DUTRA, Brian ,  MERCADO, Ari ,  KENNEDY, III, Thomas J. ,  MARTIN, Arthur

IPC分类号： C12M1/00 ,  B01D21/28

公开(公告)号：EP2953700A1

公开(公告)日：2015-12-16

申请号：EP14749278.9

申请日：2014-02-07

申请人： Flodesign Sonics Inc.

发明人： LIPKENS, Bart ,  MASI, Louis ,  KOWALSKI III, Stanley ,  PRESZ, Walter M. jr. ,  DIONNE, Jason ,  DUTRA, Brian ,  MERCADO, Ari ,  KENNEDY III, Thomas ,  MARTIN, Arthur

IPC分类号： B01D21/28

CPC分类号： C12M47/06 ,  B01D21/283 ,  C12M29/10 ,  C12M33/08 ,  C12M47/02

摘要： A perfusion bioreactor includes at least one ultrasonic transducer that can acoustically generate a multi-dimensional standing wave. The standing wave can be used to retain cells in the bioreactor, and can also be utilized to dewater or further harvest product from the waste materials produced in a bioreactor. The bioreactor includes a reaction vessel, an agitator, a feed inlet, and an outlet. A filtering device is included that has an inlet, a flow chamber and a sleeve surrounding the flow chamber, where the sleeve includes the ultrasonic transducer.

摘要翻译： 灌注生物反应器包括至少一个可声学地产生多维驻波的超声换能器。 驻波可用于将细胞保留在生物反应器中，并且还可用于从生物反应器中生产的废物中脱水或进一步收获产品。 生物反应器包括反应容器，搅拌器，进料口和出口。 包括过滤装置，其具有入口，流动室和围绕流动室的套筒，其中套筒包括超声换能器。

公开(公告)号：EP2872234A1

公开(公告)日：2015-05-20

申请号：EP13742354.7

申请日：2013-07-16

申请人： Flodesign Sonics Inc.

发明人： LIPKENS, Bart ,  DIONNE, Jason ,  MERCADO, Ari ,  DUTRA, Brian ,  PRESZ, Walter, Jr. ,  MASI, Louis ,  KENNEDY, Thomas J., III

IPC分类号： B01D17/04 ,  C02F1/36 ,  C02F1/40

CPC分类号： B01D17/045 ,  B06B1/0644 ,  C02F1/36 ,  C02F1/40 ,  C12M47/02

摘要： An acoustic standing wave is utilized to separate components from a multi- component fluid, such as oil from an oil-water mixture, in a fluid flow scheme with an acoustophoresis device. For example, the flow scheme and device allows for trapping of the oil as the oil coalesces, agglomerates, and becomes more buoyant than the water.