公开(公告)号：EP0912901A1

公开(公告)日：1999-05-06

申请号：EP97924591.0

申请日：1997-05-12

申请人： G.D. SEARLE & CO.

发明人： CARRON, Christopher, P. ,  FEIGEN, Larry, P. ,  HAAS, Neal, F. ,  MEYER, Debra, M. ,  PAGE, Jimmy, D. ,  PEGG, Jodi, Ann

IPC分类号： C12P21 ,  C07K16 ,  C12N5 ,  G01N33

CPC分类号： C07K16/44 ,  G01N33/86 ,  G01N33/94 ,  Y10S435/808 ,  Y10S435/975

摘要： A method for determining the amount of an antiplatelet compound in a subject being treated with the compound which comprises calculating the ACT number of the subject's blood containing a reagent which immunoreacts with the antiplatelet compound and comparing the figure to a standardized concentration figure. In subjects concurrently being treated with heparin and antiplatelet compounds, the method can be practiced without additional heparin added to the blood sample. The invention also provides reagents which immunoreact with antiplatelet compounds and kits comprising immunoreactive reagents.

公开(公告)号：EP0912901B1

公开(公告)日：2001-11-07

申请号：EP97924591.7

申请日：1997-05-12

申请人： G.D. SEARLE & CO.

发明人： CARRON, Christopher, P. ,  FEIGEN, Larry, P. ,  HAAS, Neal, F. ,  MEYER, Debra, M. ,  PAGE, Jimmy, D. ,  PEGG, Jodi, Ann

IPC分类号： G01N33/94 ,  C07K16/44 ,  C12N5/18

CPC分类号： C07K16/44 ,  G01N33/86 ,  G01N33/94 ,  Y10S435/808 ,  Y10S435/975

摘要： A method for determining the amount of an antiplatelet compound in a subject being treated with the compound which comprises calculating the ACT number of the subject's blood containing a reagent which immunoreacts with the antiplatelet compound and comparing the figure to a standardized concentration figure. In subjects concurrently being treated with heparin and antiplatelet compounds, the method can be practiced without additional heparin added to the blood sample. The invention also provides reagents which immunoreact with antiplatelet compounds and kits comprising immunoreactive reagents.