摘要:
A fluidized bed coating apparatus is provided and includes a fluid inlet adapted to be connected to a source of fluidizing fluid. The fluid inlet has an entrance opening having a first diameter and an exit opening downstream of the entrance opening. The exit opening has a second diameter that is larger than the first diameter. The inlet also includes an expanding inlet section, between the entrance opening and the exit opening, that has an average diameter that increases in a direction from said entrance opening to said exit opening. A fluid distribution plate is provided adjacent the exit opening and includes a plurality of through-passages to allow the even and distributed passage of a fluidizing fluid therethrough. A chamber having a chamber inlet and a chamber outlet is provided and the fluid distribution plate is positioned between the exit opening and the chamber inlet. The chamber includes at least a first diverging section having an average diameter that increases in the direction from the chamber inlet downstream toward the chamber outlet. The symmetrical design of the coater provides an evenly distributed flow of fluid that enables efficient and complete fluidization and coating of very large particle beds.
摘要:
Coatings for pharmaceutical dosage forms, food and confectionery tablets, seeds and granule cores are described. The coating includes a modified starch and a plasticizer optionally in combination with a secondary polymer. Also described is a coating including a modified starch and a secondary polymer optionally in combination with a plasticizer. Also described are coated pharmaceutical dosage forms, food and confectionery tablets, seeds and granule cores. Further described are cleaning, textile and feed compositions including the coated granule cores.
摘要:
On décrit une composition enzymatique granulaire présentant une tendance réduite à produire de la poussière ou à laisser des résidus, faisant preuve d'une stabilité améliorée et permettant la libération retardée. La composition granulaire comprend un noyau, une couche d'enzymes et une couche d'enrobage externe. La couche d'enzymes, et, éventuellement, le noyau et la couche d'enrobage contiennent un polymère vinylique. Sont également décrits des procédés de préparation de telles granules contenant des enzymes, les procédés comprenant un temps de traitement considérablement réduit.
摘要:
The present invention provides highly impact-resistant, water-soluble or water dispersible, low-dust granules comprising an active ingredient and methods for obtaining the same.
摘要:
The present invention provides an improved coating material for use with particles, such as enzyme granules, and the like. In particular, the present invention provides a modified PVA, as well as particles or granules that include such coating. The PVA is modified by substituting hydrophilic moieties for the hydroxyl or alcohol groups of the PVA. Substitution may be achieved with hydrophilic acids, amines, thiols, or combinations thereof. Detergent compositions comprising said particles with coating in combination with borates or perborates.
摘要:
Detergent formulations are prepared by directly agglomerating a fermentation broth extract, containing a detergent-type enzyme and a nonionic detergent-type surfactant, with a suitable detergent base mixture, without need for prior isolation of the enzyme.
摘要:
A granular enzyme composition is disclosed, having reduced tendencies to form dust and leave residue, and exhibiting improved stability and delayed release characteristics. The granular composition comprises a core, an enzyme layer and an outer coating layer. The enzyme layer, and optionally the core and coating layers, contain a vinyl polymer. Also disclosed are methods for making such enzyme-containing granules, the methods having greatly reduced processing time.
摘要:
The present invention provides a mechanically robust, water-soluble or water dispersible, low-dust granule comprising an active ingredient, a polymer coating, and an impregnated plasticizer within the granule, and methods for obtaining the same.