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公开(公告)号：EP2784084B1
公开(公告)日：2019-07-24
申请号：EP14163686.0
申请日：2004-06-02
申请人： Genentech, Inc.
发明人： Arnott, David , Gurney, Austin , Hass, Phillip , Lee, James , Wu, Yan
IPC分类号： C07K16/24 , A61K39/395
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公开(公告)号：EP2083079A1
公开(公告)日：2009-07-29
申请号：EP09000133.0
申请日：1998-06-12
申请人： Genentech, Inc.
发明人： Ashkenazi, Avi J. , Baker, Kevin P. , Chuntharapai, Anan , Gurney, Austin , Kim, Kyung Jin , Wood, William I.
IPC分类号： C12N15/12 , C12N15/62 , C12N5/12 , C07K14/715 , C07K16/28 , A01K67/027 , A61K38/17 , G01N33/50
CPC分类号： C07K14/70575 , A01K2217/05 , A01K2217/075 , A01K2227/105 , A61K38/00 , C07K14/70578 , C07K2319/00 , C07K2319/30
摘要： Novel polypeptides, designated Apo-2DcR, which are capable of binding Apo-2 ligand are provided. Compositions including Apo-2DcR chimeras, nucleic acid encoding Apo-2DcR, and antibodies to Apo-2DcR are also provided.
摘要翻译： 提供了能够结合Apo-2配体的新型多肽，命名为Apo-2DcR。 还提供了包括Apo-2DcR嵌合体，编码Apo-2DcR的核酸和Apo-2DcR抗体的组合物。
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公开(公告)号：EP2050762A3
公开(公告)日：2009-07-08
申请号：EP08014196.3
申请日：1999-03-08
申请人： Genentech, Inc.
发明人： Wood, William I , Goddard, Audrey , Gurney, Austin , Yuan, Jean , Baker, Kevin P. , Chen, Jian
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypetide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：EP1241179B1
公开(公告)日：2006-08-02
申请号：EP02012896.3
申请日：1999-03-08
申请人： GENENTECH, INC.
发明人： Wood, William I. , Goddard, Audrey , Gurney, Austin , Yuan, Jean , Baker, Kevin P. , Chen, Jian
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5.发明授权
公开(公告)号：EP1241252B1
公开(公告)日：2006-05-10
申请号：EP02012905.2
申请日：1999-03-08
申请人： GENENTECH, INC.
发明人： Wood, William I. , Goddard, Audrey , Gurney, Austin , Yuan, Jean , Baker, Kevin P. , Chen, Jian
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6.发明公开HUman HCAR-like protein and nucleic acids encoding it 有权Menschliches HCAR-ähnlichesProtein unddafürkodierendeNukleinsäure
公开(公告)号：EP1241183A3
公开(公告)日：2003-06-11
申请号：EP02012901.1
申请日：1999-03-08
申请人： Genentech, Inc.
发明人： Wood, William I. , Goddard, Audrey , Gurney, Austin , Yuan, Jean , Baker, Kevin P. , Chen, Jian
IPC分类号： C07K14/705 , C07K16/28 , C07K19/00 , C12N15/12 , C12N15/62
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：EP1270590A1
公开(公告)日：2003-01-02
申请号：EP02012903.7
申请日：1999-03-08
申请人： Genentech, Inc.
发明人： Wood, William I. , Goddard, Audrey , Gurney, Austin , Yuan, Jean , Baker, Kevin P. , Chen, Jian
IPC分类号： C07K14/705 , C07K16/28 , C07K19/00 , C12N15/12 , C12N15/62
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新的多肽和编码这些多肽的核酸分子。 因此，在提供的是载体和宿主细胞包含这些核酸序列，嵌合多肽分子包含本发明的多肽融合到结合本发明的多肽的异源多肽序列，抗体和方法用于制造本多肽 发明。
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公开(公告)号：EP1241252A2
公开(公告)日：2002-09-18
申请号：EP02012905.2
申请日：1999-03-08
申请人： Genentech, Inc.
发明人： Wood, William I. , Goddard, Audrey , Gurney, Austin , Yuan, Jean , Baker, Kevin P. , Chen, Jian
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：EP1241187A2
公开(公告)日：2002-09-18
申请号：EP02012898.9
申请日：1999-03-08
申请人： Genentech, Inc.
发明人： Wood, William I. , Goddard, Audrey , Gurney, Austin , Yuan, Jean , Baker, Kevin P. , Chen, Jian
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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10.发明授权Human growth arrest specific gene 6 (gas-6) and nucleic acids encoding the same 有权人类气体-6（生长停滞特异性基因6）蛋白质和核酸编码为此
公开(公告)号：EP1241186B1
公开(公告)日：2008-11-26
申请号：EP02012897.1
申请日：1999-03-08
申请人： Genentech, Inc.
发明人： Wood, William I. , Goddard, Audrey , Gurney, Austin , Yuan, Jean , Baker, Kevin P. , Chen, Jian
IPC分类号： C07K14/745 , C07K16/36 , C07K19/00 , C12N15/62 , C12Q1/68 , A61K39/395 , A61K31/7088 , G01N33/577 , G01N33/53
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