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1.发明公开CONTROL OF METABOLISM WITH COMPOSITIONS OF THE HUMAN 2-OXOGLUTARATE CARRIER 有权代谢控制借助人居在一起，2-酮戊二酸的载体
公开(公告)号：EP1294881A2
公开(公告)日：2003-03-26
申请号：EP01950401.8
申请日：2001-06-22
申请人： GENENTECH, INC.
发明人： ADAMS, Sean , YU, Xing Xian
CPC分类号： C12Q1/6883 , A01K2217/05 , A61K38/00 , A61K48/00 , C07K14/47 , C07K2319/00 , C07K2319/43 , C12Q1/6809 , C12Q2600/158 , G01N33/5008 , G01N33/502 , G01N33/5035 , G01N33/5079 , G01N2800/52
摘要： The present invention is directed to compositions and methods related to the use of human OGC as an uncoupling protein.
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公开(公告)号：EP1294877A2
公开(公告)日：2003-03-26
申请号：EP01946702.6
申请日：2001-06-22
发明人： LEWIN, David , ADAMS, Sean, H. , YU, Xing Xian
IPC分类号： C12N15/12 , C07K14/47 , C12N5/10 , C12Q1/68 , C12N15/62 , C07K16/18 , G01N33/50 , G01N33/53 , A01K67/027
CPC分类号： C12Q1/6883 , A01K2217/05 , A61K38/00 , A61K48/00 , C07K14/47 , C07K2319/00 , C07K2319/43 , C12Q1/6809 , C12Q2600/158 , G01N33/5008 , G01N33/502 , G01N33/5035 , G01N33/5079 , G01N2800/52
摘要： An isolated polypeptide comprising an amino acid sequence having at least 80 % sequence identity to the sequence SEQ ID NO:1, polynucleotides encoding these peptides, and antibodies to the polypeptides are useful in treating metabolic disorders or disorders associated with changes in adipose tissue physiological function or mass.
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公开(公告)号：EP1294877B1
公开(公告)日：2005-09-21
申请号：EP01946702.6
申请日：2001-06-22
发明人： LEWIN, David , ADAMS, Sean, H. , YU, Xing Xian
IPC分类号： C12N15/12 , C07K14/47 , C12N5/10 , C12Q1/68 , C12N15/62 , C07K16/18 , G01N33/50 , G01N33/53 , A01K67/027
CPC分类号： C12Q1/6883 , A01K2217/05 , A61K38/00 , A61K48/00 , C07K14/47 , C07K2319/00 , C07K2319/43 , C12Q1/6809 , C12Q2600/158 , G01N33/5008 , G01N33/502 , G01N33/5035 , G01N33/5079 , G01N2800/52
摘要： An isolated polypeptide comprising an amino acid sequence having at least 80 % sequence identity to the sequence SEQ ID NO:1, polynucleotides encoding these peptides, and antibodies to the polypeptides are useful in treating metabolic disorders or disorders associated with changes in adipose tissue physiological function or mass.
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4.发明授权CONTROL OF METABOLISM WITH COMPOSITIONS OF THE HUMAN 2-OXOGLUTARATE CARRIER 有权代谢控制借助人居在一起，2-酮戊二酸的载体
公开(公告)号：EP1294881B1
公开(公告)日：2004-09-15
申请号：EP01950401.8
申请日：2001-06-22
申请人： GENENTECH, INC.
发明人： ADAMS, Sean , YU, Xing Xian
CPC分类号： C12Q1/6883 , A01K2217/05 , A61K38/00 , A61K48/00 , C07K14/47 , C07K2319/00 , C07K2319/43 , C12Q1/6809 , C12Q2600/158 , G01N33/5008 , G01N33/502 , G01N33/5035 , G01N33/5079 , G01N2800/52
摘要： The present invention is directed to compositions and methods related to the use of human OGC as an uncoupling protein.
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