公开(公告)号：EP3060647A4

公开(公告)日：2017-03-22

申请号：EP14855926

申请日：2014-10-23

申请人： GENIA TECH INC

发明人： DAVIS RANDALL W ,  LIU EDWARD SHIAN ,  HARADA ERIC TAKESHI ,  AGUIRRE ANNE ,  TRANS ANDREW ,  POLLARD JAMES ,  CECH CYNTHIA

IPC分类号： C12M1/34 ,  B05D5/12 ,  C12Q1/68 ,  G01N33/487

CPC分类号： C12Q1/6869 ,  C12M1/34 ,  G01N27/3277 ,  G01N27/3278 ,  G01N27/44791 ,  G01N33/48721 ,  C12Q2565/607 ,  C12Q2565/631

摘要： This disclosure provides a biochip comprising a plurality of wells. The biochip includes a membrane that is disposed in or adjacent to an individual well of the plurality of wells. The membrane comprises a nanopore, and the individual well comprises an electrode that detects a signal upon ionic flow through the pore in response to a species passing through or adjacent to the nanopore. The electrode can be a non-sacrificial electrode. A lipid bilayer can be formed over the plurality of wells using a bubble.

公开(公告)号：EP3060646A4

公开(公告)日：2017-06-21

申请号：EP14855736

申请日：2014-10-23

申请人： GENIA TECH INC

发明人： DAVIS RANDALL W ,  LIU EDWARD SHIAN ,  HARADA ERIC TAKESHI ,  AGUIRRE ANNE ,  TRANS ANDREW ,  POLLARD JAMES ,  CECH CYNTHIA

IPC分类号： C12M1/34 ,  B05D5/12 ,  C12Q1/68 ,  G01N33/487

CPC分类号： C12Q1/6869 ,  C12M1/34 ,  G01N27/3277 ,  G01N27/3278 ,  G01N27/44791 ,  G01N33/48721 ,  C12Q2565/607 ,  C12Q2565/631

摘要： This disclosure provides a biochip comprising a plurality of wells. The biochip includes a membrane that is disposed in or adjacent to an individual well of the plurality of wells. The membrane comprises a nanopore, and the individual well comprises an electrode that detects a signal upon ionic flow through the pore in response to a species passing through or adjacent to the nanopore. The electrode can be a non-sacrificial electrode. A lipid bilayer can be formed over the plurality of wells using a bubble.

摘要翻译： 本公开提供了包括多个井的生物芯片。 生物芯片包括设置在多个井的单个井中或与其相邻的膜。 所述膜包含纳米孔，并且所述单独的孔包含电极，所述电极响应于穿过或邻近所述纳米孔的物质而在离子流过所述孔时检测信号。 电极可以是非牺牲电极。 可以使用气泡在多个孔上形成脂质双分子层。