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    METAL ION DETECTION METHOD, ANALYTE DETECTION METHOD, ELECTRODE SUBSTRATE, AND DETECTION KIT
    4.
    发明公开
    METAL ION DETECTION METHOD, ANALYTE DETECTION METHOD, ELECTRODE SUBSTRATE, AND DETECTION KIT 审中-公开
    金属离子检测方法，分析物检测方法，电极基质和检测试剂盒

    公开(公告)号：EP3249396A1

    公开(公告)日：2017-11-29

    申请号：EP16740169.4

    申请日：2016-01-19

    申请人： Sysmex Corporation

    发明人： HORI, Nobuyasu ,  KIRIMURA, Hiroya ,  TAKAMURA, Yuzuru ,  CHIKAE, Miyuki

    IPC分类号： G01N27/48 ,  G01N27/327 ,  G01N27/416

    CPC分类号： G01N27/42 ,  G01N27/327 ,  G01N27/3277 ,  G01N27/416 ,  G01N27/48 ,  G01N33/54313 ,  G01N33/5438 ,  G01N33/553

    摘要： Provided is a method for detecting a test substance. In this method, metal is deposited or a complex containing a test substance and a metal particle is immobilized on a working electrode on an electrode substrate including the working electrode and a counter electrode. An oxidation potential is applied to the working electrode to generate metal ions, then a reduction potential is applied to a portion having an area smaller than an area of the portion to which an oxidation potential is applied in the working electrode to deposit metal on the surface of the portion to which the reduction potential is applied, and current, voltage or charge caused by the metal deposited is measured to detect metal ions or a test substance.

    摘要翻译： 提供了一种用于检测测试物质的方法。 在该方法中，在包括工作电极和反电极的电极基板上，沉积金属或者将包含测试物质和金属颗粒的复合物固定在工作电极上。 对工作电极施加氧化电位以产生金属离子，然后在工作电极上的面积小于施加氧化电位的部分的面积的部分施加还原电位，以使金属沉积在表面上 测量施加还原电位的部分，测量由沉积的金属引起的电流，电压或电荷，以检测金属离子或测试物质。

    MATRIX-ENHANCED ELECTROCHEMICAL DETECTOR FOR PATHOGENIC BACTERIA
    5.
    发明公开
    MATRIX-ENHANCED ELECTROCHEMICAL DETECTOR FOR PATHOGENIC BACTERIA 审中-公开
    MATRIXERWEITERTER ELEKTROCHEMISCHER DETEKTOR PATHOGENER BAKTERIEN

    公开(公告)号：EP3039733A4

    公开(公告)日：2017-05-31

    申请号：EP14840167

    申请日：2014-08-29

    申请人： UNIV NORTHEASTERN

    发明人： GOLUCH EDGAR D ,  SISMAET HUNTER J ,  WEBSTER THADDAEUS A

    IPC分类号： H01M4/02 ,  G01N27/327 ,  G01N33/487

    CPC分类号： G01N27/3275 ,  B01L3/502707 ,  B01L3/502715 ,  B01L2300/0645 ,  B01L2300/0861 ,  B01L2300/0896 ,  G01N27/3277 ,  G01N33/48728 ,  G01N33/48735 ,  G01N2333/21

    摘要： Devices for electrochemical measurement of a redox active substance secreted by a cell in a liquid sample are provided. The devices include one or more electrodes and a matrix capable of releasing a chemical agent that stimulates secretes of the redox active substance by the cell. In some embodiments, the devices include a nanofluidic electrode assembly in which the one or more electrodes are disposed within a nanofluidic channel. Methods of fabricating the devices and methods of using the devices to detect secretion of a redox active substance by a cell are also provided.

    摘要翻译： 提供了用于电化学测量由液体样品中的细胞分泌的氧化还原活性物质的装置。 该装置包括一个或多个电极和能够释放刺激细胞分泌氧化还原活性物质的化学试剂的基质。 在一些实施例中，所述装置包括纳米流体电极组件，其中所述一个或多个电极布置在纳米流体通道内。 还提供了制造装置的方法和使用该装置检测细胞分泌氧化还原活性物质的方法。

    ELECTROCHEMICAL BIOSENSOR WITH IMPROVED ACCURACY
    7.
    发明公开
    ELECTROCHEMICAL BIOSENSOR WITH IMPROVED ACCURACY 有权
    ELEKTROCHEMISCHER生物传感器MIT VERBESSERTER GENAUIGKEIT

    公开(公告)号：EP2871470A1

    公开(公告)日：2015-05-13

    申请号：EP13796996.0

    申请日：2013-05-31

    申请人： i-Sens, Inc.

    发明人： LEE, Myeong Ho ,  KIM, Moon Hwan ,  LEE, Ung Ki ,  PARK, Han Be ,  JUNG, Sung-Kwon ,  NAM, Hakhyun ,  CHA, Geun Sig

    IPC分类号： G01N27/30 ,  G01N33/66

    CPC分类号： G01N27/3277 ,  C12Q1/006 ,  G01N27/3272 ,  G01N27/3274 ,  G01N33/66

    摘要： The present invention relates to an electrochemical biosensor with improved hematocrit measurement accuracy for measuring blood glucose. According to the present invention, an electrochemical biosensor including a first electrode part for correcting a measured hematocrit value and a second electrode part for measuring a glucose concentration is effective in improving accuracy of a measured hematocrit value and in more improving accuracy of a measured blood glucose concentration using the measured hematocrit values for correction, because an insulation cover is made thinner than a working electrode and an auxiliary electrode, so that areas of a first working electrode and a first auxiliary electrode of the first electrode part exposed to a blood sample become equal; a distance between the first working electrode and the second working electrode becomes constant; and electrode areas are maintained constantly by the insulation cover even when a positioning error occurs during printing.

    摘要翻译： 本发明涉及一种具有改善血细胞比容测量精度的电化学生物传感器，用于测量血糖。 根据本发明，包括用于校正测量的血细胞比容值的第一电极部分和用于测量葡萄糖浓度的第二电极部分的电化学生物传感器有效地提高测量的血细胞比容值的精度，并且更有效地提高测量血糖的精度 由于绝缘覆盖物比工作电极和辅助电极薄，所以第一电极部分暴露于血液样本的第一工作电极和第一辅助电极的面积变得相等，因此使用测量的血细胞比容值进行校正。 ; 第一工作电极和第二工作电极之间的距离变得恒定; 并且即使在打印期间发生定位误差，电极区域也由绝缘盖保持恒定。

    ELEKTRODENANORDNUNG UND VERFAHREN ZUM BETREIBEN DER ELEKTRODENANORDNUNG
    9.
    发明公开
    ELEKTRODENANORDNUNG UND VERFAHREN ZUM BETREIBEN DER ELEKTRODENANORDNUNG 审中-公开
    电极装置及其操作方法之一的电极装置

    公开(公告)号：EP2737307A1

    公开(公告)日：2014-06-04

    申请号：EP12748153.9

    申请日：2012-06-12

    申请人： Forschungszentrum Jülich Gmbh

    发明人： MAYER, Dirk ,  LIU, Yaqing ,  OFFENHÄUSSER, Andreas

    IPC分类号： G01N27/403 ,  H01L51/05 ,  H01L51/10

    CPC分类号： G01N27/27 ,  G01N27/3277

    摘要： The invention relates to an electrode arrangement for the cyclic reduction and oxidation of a redox species in an electrolyte, wherein both electrodes are arranged on an insulating substrate and are connected to apply a voltage to a counter-electrode, comprising: a) a control electrode for reacting the redox species for a cyclic electron transport between the electrodes, and b) a collector electrode arranged opposite the control electrode, wherein a layer structure comprising a second insulator and a charge transfer mediator arranged thereon for reacting the redox species is additionally arranged on the side of the collector electrode opposite the insulating substrate. The invention relates to two methods for operating the electrode arrangement.

    METHOD AND APPARATUS FOR MEASURING OXIDATION-REDUCTION POTENTIAL
    10.
    发明公开
    METHOD AND APPARATUS FOR MEASURING OXIDATION-REDUCTION POTENTIAL 有权
    VORRICHTUNG ZUR MESSUNG EINES REDOXPOTENTIALS

    公开(公告)号：EP2681543A1

    公开(公告)日：2014-01-08

    申请号：EP12714103.4

    申请日：2012-02-28

    申请人： Luoxis Diagnostics, Inc.

    发明人： BAR-OR, Raphael ,  BAR-OR, David ,  RAEL, Leonard, T.

    IPC分类号： G01N27/30 ,  G01N27/416

    CPC分类号： G01N27/3277 ,  G01N27/301 ,  G01N27/3272 ,  G01N27/403 ,  G01N27/4168 ,  G01N33/49

    摘要： Methods and systems for measuring the oxidation-reduction potential of a fluid sample are provided. The system includes a test strip with a sample chamber adapted to receive a fluid sample. The sample chamber can be associated with a filter membrane. The test strip also includes a reference cell. The oxidation-reduction potential of a fluid sample placed in the sample chamber can be read by a readout device interconnected to a test lead that is in electrical contact with the sample chamber, and a reference lead that is in electrical contact with the reference cell. Electrical contact between a fluid sample placed in the sample chamber and the reference cell can be established by a bridge. The bridge may comprise filter element such as a piece of filter paper that is wetted, for example by the fluid sample, or an electrolytic gel. The oxidation-reduction potential may be read as an electrical potential between the test lead and the reference lead of the test strip.

    摘要翻译： 提供了用于测量流体样品的氧化还原电位的方法和系统。 该系统包括具有适于接收流体样品的样品室的测试条。 样品室可以与过滤膜相关联。 测试条还包括参考单元。 放置在样品室中的流体样品的氧化还原电位可以通过互连到与样品室电接触的测试导线的读出装置读取，以及与参考电池电接触的参考引线。 放置在样品室中的流体样品与参考单元之间的电接触可通过桥来建立。 氧化还原电位可以被读取为测试引线与测试条的参考引线之间的电位。