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公开(公告)号:EP2234634A2
公开(公告)日:2010-10-06
申请号:EP08859440.3
申请日:2008-12-11
申请人: GENVEC, INC. , The Government Of The USA, As Represented By The Secretary, Dept. Of Health & Human Services
IPC分类号: A61K39/00
CPC分类号: A61K39/235 , A61K39/12 , A61K2039/5254 , C12N2710/10334
摘要: The invention is directed to a live attenuated serotype 14 adenovirus, and a method of inducing an immune response against a serotype 14 adenovirus in a mammal using the live attenuated serotype 14 adenovirus.
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公开(公告)号:EP2498791B1
公开(公告)日:2014-12-24
申请号:EP10782478.1
申请日:2010-11-09
申请人: GenVec, Inc.
发明人: GALL, Jason , BROUGH, Douglas , KAHL, Christoph , MCVEY, Duncan
IPC分类号: A61K35/76
CPC分类号: C07K14/005 , C12N7/00 , C12N15/86 , C12N2710/10322 , C12N2710/10332 , C12N2710/10343 , C12N2710/10352
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公开(公告)号:EP2498791A2
公开(公告)日:2012-09-19
申请号:EP10782478.1
申请日:2010-11-09
申请人: GenVec, Inc.
发明人: GALL, Jason , BROUGH, Douglas , KAHL, Christoph , MCVEY, Duncan
IPC分类号: A61K35/76
CPC分类号: C07K14/005 , C12N7/00 , C12N15/86 , C12N2710/10322 , C12N2710/10332 , C12N2710/10343 , C12N2710/10352
摘要: The invention provides methods for propagating a monkey adenovirus in a cell including a human cell, comprising one or more gene products isolated from a human adenovirus. Also provided are methods for propagating wherein the monkey adenovirus comprises a nucleic acid sequence encoding a human adenovirus gene product. The invention further provides a monkey adenovirus. including a replication-deficient monkey adenovirus, obtained by such propagation methods.
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