专利检索 ap:("GLAXO GROUP LIMITED") AND inv:"GELLIBERT, Francoise, Jeanne" 第 1 页

1.

发明公开
2-AMINO-4-(PYRIDIN-2-YL)-THIAZOLE DERIVATIVES AS TRANSFORMING GROWTH FACTOR BETA (TGF-BETA) INHIBITORS 审中-公开
标题翻译： 2-氨基-4-（吡啶-2-基）噻唑衍生物ALS抑制剂转化生长因子BET（TGF-βA）

公开(公告)号：EP1355892A1

公开(公告)日：2003-10-29

申请号：EP02710053.6

申请日：2002-01-30

申请人： GLAXO GROUP LIMITED

发明人： GELLIBERT, Francoise, Jeanne , HARTLEY, Charles, David , MATHEWS, Neil , WOOLVEN, James, Michael

IPC分类号： C07D277/42 , C07D417/14 , A61K31/425 , A61P1/16

CPC分类号： C07D417/14 , C07D471/04

摘要： Therapeutically active thiazole derivatives of formula (I) wherein R1, R2, X and X' are as defined in the specification, processes for the preparation thereof, the use thereof in therapy, particularly in the treatment or prophylaxis of disorders characterised by overexpression of transforming growth factor β (TGF-β), and pharmaceutical compositions for use in such therapy. (I)