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公开(公告)号：EP0117064B1
公开(公告)日：1990-08-08
申请号：EP84300316.1
申请日：1984-01-19
IPC分类号： A61L2/04
CPC分类号： A61K38/37 , A61K31/14 , A61L2/0023 , A61L2/04
摘要： Heat treatment of an aqueous solution or a fraction containing blood coagulation factor VIII to inactivate hepatitis viruses is carried out in the presence of a stabilizer selected from sugar-alcohols or disaccharides in a concentration of at least 1.5 g per ml of the acqueous solution or fraction.
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公开(公告)号：EP0098073A3
公开(公告)日：1985-09-25
申请号：EP83303426
申请日：1983-06-14
CPC分类号： A61K9/0014 , A61K9/0019 , A61K38/44 , A61K47/12 , C12Y111/02002
摘要： A powdery pharmaceutical composition of myeloperoxidase comprises myeloperoxidase and an amount, enough to stabilize the myeloperoxidase, of citric acid or a salt thereof.
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3.发明公开
公开(公告)号：EP0098073A2
公开(公告)日：1984-01-11
申请号：EP83303426.7
申请日：1983-06-14
CPC分类号： A61K9/0014 , A61K9/0019 , A61K38/44 , A61K47/12 , C12Y111/02002
摘要： A powdery pharmaceutical composition of myeloperoxidase comprises myeloperoxidase and an amount, enough to stabilize the myeloperoxidase, of citric acid or a salt thereof.
摘要翻译： 髓过氧化物酶的粉末状药物组合物包括髓过氧化物酶和足以稳定髓过氧化物酶的柠檬酸或其盐的量。
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公开(公告)号：EP0117064A3
公开(公告)日：1985-04-17
申请号：EP84300316
申请日：1984-01-19
CPC分类号： A61K38/37 , A61K31/14 , A61L2/0023 , A61L2/04
摘要： Heat treatment of an aqueous solution or a fraction containing blood coagulation factor VIII to inactivate hepatitis viruses is carried out in the presence of a stabilizer selected from sugar-alcohols or disaccharides in a concentration of at least 1.5 g per ml of the acqueous solution or fraction.
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5.发明公开Process for heat treatment of blood coagulation factor VIII 失效Verfahren zur Hitzebehandlung vom Blutgerinnungsfaktor VIII。
公开(公告)号：EP0117064A2
公开(公告)日：1984-08-29
申请号：EP84300316.1
申请日：1984-01-19
IPC分类号： A61L2/04
CPC分类号： A61K38/37 , A61K31/14 , A61L2/0023 , A61L2/04
摘要： Heat treatment of an aqueous solution or a fraction containing blood coagulation factor VIII to inactivate hepatitis viruses is carried out in the presence of a stabilizer selected from sugar-alcohols or disaccharides in a concentration of at least 1.5 g per ml of the acqueous solution or fraction.
摘要翻译： 含有凝血因子VIII以使灭活肝炎病毒的水溶液或级分的热处理是在选自糖醇或二糖的稳定剂存在下进行的，所述糖醇或二糖的浓度为至少1.5g / ml水溶液或级分 。
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公开(公告)号：EP0098073B1
公开(公告)日：1988-12-14
申请号：EP83303426.7
申请日：1983-06-14
CPC分类号： A61K9/0014 , A61K9/0019 , A61K38/44 , A61K47/12 , C12Y111/02002
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