专利检索 ap:("GTC BIOTHERAPEUTICS INC") AND inv:"MELICAN DAVID" 第 1 页

1.

发明公开
A METHOD FOR SELECTING CELL LINES TO BE USED FOR NUCLEAR TRANSFER IN MAMMALIAN SPECIES 审中-公开
标题翻译：程序用于选择哺乳动物物种中核传输中使用细胞系

公开(公告)号：EP1490487A4

公开(公告)日：2007-08-29

申请号：EP03723815

申请日：2003-03-25

申请人： GTC BIOTHERAPEUTICS INC

发明人： MELICAN DAVID , BUTLER ROBIN E , GAVIN WILLIAM G

IPC分类号： A01K67/027 , A01K67/00 , C12N5/02 , C12N5/10 , C12N15/09 , C12N15/877 , C12N15/00 , C12N5/00 , C12N15/63 , C12N15/70 , C12N15/74 , C12N15/85 , C12N15/87

CPC分类号： C12N15/8772 , A01K67/00

摘要： The present invention provides data to demonstrate that the fusion performance of a cell-line in procedures involving fusion and cleavage indices either alone or in combination are a means for selecting a cell lines that will be successful in a nuclear transfer or microinjection program. This technique and method of selecting a cell line offers an additional alternative and improvement in the creation of activated and fused nuclear transfer-capable embryos for the production of live offspring in various mammalian non-human species including goats, pigs, rodents, primates, rabbits and cattle.