公开(公告)号：EP2888226A1

公开(公告)日：2015-07-01

申请号：EP12780547.1

申请日：2012-09-28

申请人： Galaxy Surfactants Ltd.

发明人： KOSHTI, Nirmal ,  PARAB, Bharat, Bhikaji ,  POWALE, Rajendra, Subhash ,  DESAI, Archana, Kishor ,  BARAI, Kamlesh, Keshwar ,  KATDARE, Pradnya, Mandar ,  SAWANT, Bhagyesh, Jagannath ,  KADAM, Santosh, Vishnu ,  PILLI, Srinivas, Uppalaswamy

IPC分类号： C07C231/02 ,  C07C303/22 ,  C07C303/26 ,  C07C51/60 ,  C07C233/47 ,  C07C309/15 ,  C07C53/42 ,  C07C309/00

CPC分类号： C07C231/02 ,  C07C51/60 ,  C07C303/22 ,  C07C303/26 ,  C07C233/47 ,  C07C309/15 ,  C07C309/00 ,  C07C53/38

摘要： A process of producing
N -acyl amino acid based surfactants of Formula (I), wherein, R is selected from C6 to C22 alkyl group, R
1 is selected from H, C1 to C4 alkyl, R
2 is selected from all groups on a carbon of natural amino acids, R
3 is selected from COOX, CH
2 -SO
3 X, X is selected from Li
+ , Na
+ or K
+ ; said process comprising steps of A) preparing fatty acid chlorides by halogenating fatty acids with either phosgene or thionyl chloride in the presence of catalytic amount of same or other
N -acyl amino acid surfactant of Formula (I) or anhydrides of same surfactant, Formula (II), wherein, R = C6 to C22 alkyl group, R
1 = H, C1 to C4 alkyl, R
2 = all groups on α carbon of natural amino acids, n = 0 to 4, X = C, SO and B) reacting fatty acid chloride of step (A) with an amino acid in the presence of a base under typical aqueous Schotten Baumann conditions such that said process does not employ a step of purification.

公开(公告)号：EP2888226B2

公开(公告)日：2019-07-03

申请号：EP12780547.1

申请日：2012-09-28

申请人： Galaxy Surfactants Ltd.

发明人： KOSHTI, Nirmal ,  PARAB, Bharat, Bhikaji ,  POWALE, Rajendra, Subhash ,  DESAI, Archana, Kishor ,  BARAI, Kamlesh, Keshwar ,  KATDARE, Pradnya, Mandar ,  SAWANT, Bhagyesh, Jagannath ,  KADAM, Santosh, Vishnu ,  PILLI, Srinivas, Uppalaswamy

IPC分类号： C07C231/02 ,  C07C303/22 ,  C07C303/26 ,  C07C51/60 ,  C07C233/47 ,  C07C309/15 ,  C07C53/42 ,  C07C309/00

公开(公告)号：EP2888226B1

公开(公告)日：2016-07-20

申请号：EP12780547.1

申请日：2012-09-28

申请人： Galaxy Surfactants Ltd.

发明人： KOSHTI, Nirmal ,  PARAB, Bharat, Bhikaji ,  POWALE, Rajendra, Subhash ,  DESAI, Archana, Kishor ,  BARAI, Kamlesh, Keshwar ,  KATDARE, Pradnya, Mandar ,  SAWANT, Bhagyesh, Jagannath ,  KADAM, Santosh, Vishnu ,  PILLI, Srinivas, Uppalaswamy

IPC分类号： C07C231/02 ,  C07C303/22 ,  C07C303/26 ,  C07C51/60 ,  C07C233/47 ,  C07C309/15 ,  C07C53/42 ,  C07C309/00

CPC分类号： C07C231/02 ,  C07C51/60 ,  C07C303/22 ,  C07C303/26 ,  C07C233/47 ,  C07C309/15 ,  C07C309/00 ,  C07C53/38

摘要： A process of producing N-acyl amino acid based surfactants of Formula I, wherein, R is selected from C6 to C22 alkyl group, R1 is selected from H, C1 to C4 alkyl, R2 is selected from all groups on α carbon of natural amino acids, R3 is selected from COOX, CH2—SO3X, X is selected from Li+, Na+ or K+. The process comprising steps of: A) preparing fatty acid chlorides by halogenating fatty acids with either phosgene or thionyl chloride in the presence of catalytic amount of same or other N-acyl amino acid surfactant of Formula I or anhydrides of same surfactant; and B) reacting fatty acid chloride of step (A) with an amino acid in the presence of a base.

摘要翻译： I，worin R选自C6选择为C22的烷基，R 1选自H，C 1选择为C4烷基的式生产N-酰基氨基酸类表面活性剂的方法，R 2是从所有组中选择的天然氨基酸的α碳 酸，R 3选自COOX选择，SO 3 X-CH 2，X是选自Li +，Na +或K +选择。 该方法包括步骤：A）通过卤化脂肪酸与碳酰氯或亚硫酰氯制备脂肪酸氯化物无论是在公式的相同或其他的N-酰基氨基酸表面活性剂的酸催化量的存在的I或相同的表面活性剂的酸酐; 和b）使脂肪酸与步骤（A的氯化物）在氨基酸在碱的存在下进行。